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Now showing items 51-60 of 161
Metabolic syndrome and inflammatory responses to long-term particulate air pollutants
(National Institute of Environmental Health Sciences, 2008)
Background: Human data linking inflammation with long-term particulate matter (PM) exposure are still lacking. Emerging evidence suggests that people with metabolic syndrome (MS) may be a more susceptible population. ...
Effect Modification of Air Pollution on Urinary 8-Hydroxy-2'-Deoxyguanosine by Genotypes: An Application of the Multiple Testing Procedure to Identify Significant SNP Interactions
(BioMed Central, 2010)
Background: Air pollution is associated with adverse human health, but mechanisms through which pollution exerts effects remain to be clarified. One suggested pathway is that pollution causes oxidative stress. If so, ...
A Case–Control Analysis of Exposure to Traffic and Acute Myocardial Infarction
(National Institute of Environmental Health Sciences, 2006)
Background: Long-term exposure to particulate air pollution has been associated with an increased risk of dying from cardiopulmonary and ischemic heart disease, yet few studies have evaluated cardiovascular end points other ...
Medium-Term Exposure to Traffic-Related Air Pollution and Markers of Inflammation and Endothelial Function
(National Institute of Environmental Health Sciences, 2011)
Background: Exposure to traffic-related air pollution (TRAP) contributes to increased cardiovascular risk. Land-use regression models can improve exposure assessment for TRAP. Objectives: We examined the association between ...
Searching for Sharp Drops in the Incidence of Pandemic A/H1N1 Influenza by Single Year of Age
(Public Library of Science, 2012)
Background: During the 2009 H1N1 pandemic (pH1N1), morbidity and mortality sparing was observed among the elderly population; it was hypothesized that this age group benefited from immunity to pH1N1 due to cross-reactive ...
Acute and Chronic Effects of Particles on Hospital Admissions in New England
(Public Library of Science, 2012)
Background: Many studies have reported significant associations between exposure to \(PM_{2.5}\) and hospital admissions, but all have focused on the effects of short-term exposure. In addition all these studies have relied ...
Alert Threshold Algorithms and Malaria Epidemic Detection
(Centers for Disease Control and Prevention, 2004)
We describe a method for comparing the ability of different alert threshold algorithms to detect malaria epidemics and use it with a dataset consisting of weekly malaria cases collected from health facilities in 10 districts ...
Lead Concentrations in Relation to Multiple Biomarkers of Cardiovascular Disease: The Normative Aging Study
(National Institute of Environmental Health Sciences, 2012)
Background: Lead exposure has been associated with cardiovascular disease (CVD) in animal and human studies. However, the mechanisms of action have not been fully elucidated. We therefore examined the relationship between ...
Alu and LINE-1 methylation and lung function in the normative ageing study
(BMJ Publishing Group, 2012)
Objectives: To investigate the association between methylation of transposable elements Alu and long-interspersed nuclear elements (LINE-1) and lung function. Design: Cohort study. Setting: Outpatient Veterans Administration ...