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Ambient air pollution, lung function, and airway responsiveness in asthmatic children
(Elsevier BV, 2016)
Background:
Although ambient air pollution has been linked to reduced lung function in healthy children, longitudinal analyses of pollution effects in asthma are lacking.
Objective:
To investigate pollution effects in ...
Particulate Air Pollution and Fasting Blood Glucose in Nondiabetic Individuals: Associations and Epigenetic Mediation in the Normative Aging Study, 2000–2011
(National Institute of Environmental Health Sciences, 2016)
Background: Among nondiabetic individuals, higher fasting blood glucose (FBG) independently predicts diabetes risk, cardiovascular disease, and dementia. Ambient PM2.5 (particulate matter with aerodynamic diameter ≤ 2.5 ...
Blood Epigenetic Age may Predict Cancer Incidence and Mortality
(Elsevier, 2016)
Biological measures of aging are important for understanding the health of an aging population, with epigenetics particularly promising. Previous studies found that tumor tissue is epigenetically older than its donors are ...
The impact of weather changes on air quality and health in the United States in 1994–2012
(2016)
Air quality is heavily influenced by weather conditions. In this study, we assessed the impact of long-term weather changes on air quality and health in the US during 1994–2012. We quantified past weather-related increases, ...
Lead-Related Genetic Loci, Cumulative Lead Exposure and Incident Coronary Heart Disease: The Normative Aging Study
(Public Library of Science, 2016)
Background: Cumulative exposure to lead is associated with cardiovascular outcomes. Polymorphisms in the δ-aminolevulinic acid dehydratase (ALAD), hemochromatosis (HFE), heme oxygenase-1 (HMOX1), vitamin D receptor (VDR), ...
Estimating Causal Effects of Long-Term PM2.5 Exposure on Mortality in New Jersey
(National Institute of Environmental Health Sciences, 2016)
Background: Many studies have reported the associations between long-term exposure to PM2.5 and increased risk of death. However, to our knowledge, none has used a causal modeling approach or controlled for long-term ...
Heat stroke admissions during heat waves in 1,916 US counties for the period from 1999 to 2010 and their effect modifiers
(BioMed Central, 2016)
Background: Heat stroke is a serious heat-related illness, especially among older adults. However, little is known regarding the spatiotemporal variation of heat stroke admissions during heat waves and what factors modify ...
Dietary anthocyanin intake and age-related decline in lung function: longitudinal findings from the VA Normative Aging Study123
(American Society for Nutrition, 2016)
Background: It is unknown whether habitual intake of dietary flavonoids, known for their antioxidative and anti-inflammatory properties, affects longitudinal change in lung function. Objective: We investigated whether ...
Air pollution exposure and gestational diabetes mellitus among pregnant women in Massachusetts: a cohort study
(BioMed Central, 2016)
Background: Rodent and human studies suggest an association between air pollution exposure and type 2 diabetes mellitus, but the extent to which air pollution is associated with gestational diabetes mellitus (GDM) is less ...
Ambient particulate matter and microRNAs in extracellular vesicles: a pilot study of older individuals
(BioMed Central, 2016)
Background: Air pollution from particulate matter (PM) has been linked to cardiovascular morbidity and mortality; however the underlying biological mechanisms remain to be uncovered. Gene regulation by microRNAs (miRNAs) ...