Stereochemical and Skeletal Diversity Arising from Amino Propargylic Alcohols

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Stereochemical and Skeletal Diversity Arising from Amino Propargylic Alcohols

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Title: Stereochemical and Skeletal Diversity Arising from Amino Propargylic Alcohols
Author: Kaya, Taner; Clemons, Paul A.; Pizzirani, Daniela; Schreiber, Stuart L.

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Citation: Pizzirani, Daniela, Taner Kaya, Paul A. Clemons, and Stuart L. Schreiber. 2010. Stereochemical and Skeletal Diversity Arising from Amino Propargylic Alcohols. Organic Letters 12(12): 2822-2825.
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Abstract: An efficient synthetic pathway to the possible stereoisomers of skeletally diverse heterocyclic small molecules is presented. The change in shape brought about by different intramolecular cyclizations of diastereoisomeric amino propargylic alcohols is quantified using principal moment-of-inertia (PMI) shape analysis.
Published Version: http://dx.doi.org/10.1021/ol100914b
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2883853/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Open Access Policy Articles, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#OAP
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:4457725
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