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dc.contributor.authorSeiler, Kathleen Petri
dc.contributor.authorGeorge, Gregory A.
dc.contributor.authorHapp, Mary Pat
dc.contributor.authorBodycombe, Nicole E.
dc.contributor.authorCarrinski, Hyman A.
dc.contributor.authorNorton, Stephanie
dc.contributor.authorBrudz, Steve
dc.contributor.authorSerrano, Martin
dc.contributor.authorFerraiolo, Paul
dc.contributor.authorTolliday, Nicola J.
dc.contributor.authorClemons, Paul A.
dc.contributor.authorSullivan, John P.
dc.contributor.authorMuhlich, Jeremy
dc.contributor.authorSchreiber, Stuart L.
dc.date.accessioned2010-10-06T14:52:53Z
dc.date.issued2008
dc.identifier.citationSeiler, Kathleen Petri, Gregory A. George, Mary Pat Happ, Nicole E. Bodycombe, Hyman A. Carrinski, Stephanie Norton, Steve Brudz, et al. 2008. ChemBank: a small-molecule screening and cheminformatics resource database. Nucleic Acids Research 36(Supp. 1, Database issue): D351-D359.en_US
dc.identifier.issn0305-1048en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:4459224
dc.description.abstractChemBank (http://chembank.broad.harvard.edu/) is a public, web-based informatics environment developed through a collaboration between the Chemical Biology Program and Platform at the Broad Institute of Harvard and MIT. This knowledge environment includes freely available data derived from small molecules and small-molecule screens and resources for studying these data. ChemBank is unique among small-molecule databases in its dedication to the storage of raw screening data, its rigorous definition of screening experiments in terms of statistical hypothesis testing, and its metadata-based organization of screening experiments into projects involving collections of related assays. ChemBank stores an increasingly varied set of measurements derived from cells and other biological assay systems treated with small molecules. Analysis tools are available and are continuously being developed that allow the relationships between small molecules, cell measurements, and cell states to be studied. Currently, ChemBank stores information on hundreds of thousands of small molecules and hundreds of biomedically relevant assays that have been performed at the Broad Institute by collaborators from the worldwide research community. The goal of ChemBank is to provide life scientists unfettered access to biomedically relevant data and tools heretofore available primarily in the private sector.en_US
dc.description.sponsorshipChemistry and Chemical Biologyen_US
dc.language.isoen_USen_US
dc.publisherOxford University Pressen_US
dc.relation.isversionofdoi:10.1093/nar/gkm843en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC2238881/pdf/en_US
dash.licenseLAA
dc.titleChemBank: A Small-Molecule Screening and Cheminformatics Resource Databaseen_US
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden_US
dc.relation.journalNucleic Acids Research Supplementen_US
dash.depositing.authorSchreiber, Stuart L.
dc.date.available2010-10-06T14:52:53Z
dc.identifier.doi10.1093/nar/gkm843*
dash.authorsorderedfalse
dash.contributor.affiliatedMuhlich, Jeremy
dash.contributor.affiliatedSchreiber, Stuart


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