Enhanced Negative Feedback Responses in Remitted Depression

DSpace/Manakin Repository

Enhanced Negative Feedback Responses in Remitted Depression

Citable link to this page


Title: Enhanced Negative Feedback Responses in Remitted Depression
Author: Pizzagalli, Diego; Meites, Tiffany M.; Deveney, Christen M.; Holmes, Avram J.; Bogdan, Ryan; Steele, Katherine T.; Santesso, Diane L.

Note: Order does not necessarily reflect citation order of authors.

Citation: Santesso, Diane L., Katherine T. Steele, Ryan Bogdan, Avram J. Holmes, Christen M. Deveney, Tiffany M. Meites, and Diego A. Pizzagalli. 2008. Enhanced negative feedback responses in remitted depression. Neuroreport 19, no. 10: 1045-1048.
Full Text & Related Files:
Abstract: Major depressive disorder (MDD)is characterized by hypersensitivity to negative feedback that might involve frontocingulate dysfunction. MDD patients exhibit enhanced electrophysiological responses to negative internal (errors) and external (feedback) cues. Whether this dysfunction extends to remitted depressed (RD) individuals with a history of MDD is currently unknown. To address this issue, we examined the feedback-related negativity in RD and control participants using a probabilistic punishment learning task. Despite equivalent behavioral performance, RD participants showed larger feedback-related negativities to negative feedback relative to controls; group differences remained after accounting for residual anxiety and depressive symptoms. The present findings suggest that abnormal responses to negative feedback extend to samples at increased risk for depressive episodes in the absence of current symptoms.
Published Version: http://dx.doi.org/10.1097/WNR.0b013e3283036e73
Terms of Use: This article is made available under the terms and conditions applicable to Open Access Policy Articles, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#OAP
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:4481367
Downloads of this work:

Show full Dublin Core record

This item appears in the following Collection(s)


Search DASH

Advanced Search