Little Evidence for Genetic Susceptibility to Influenza A (H5N1) from Family Clustering Data

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Little Evidence for Genetic Susceptibility to Influenza A (H5N1) from Family Clustering Data

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Title: Little Evidence for Genetic Susceptibility to Influenza A (H5N1) from Family Clustering Data
Author: Pitzer, Virginia E.; Olsen, Sonja J.; Bergstrom, Carl T.; Dowell, Scott F.; Lipsitch, Marc

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Citation: Pitzer, Virginia E., Sonja J. Olsen, Carl T. Bergstrom, Scott F. Dowell, and Marc Lipsitch. 2007. Little evidence for genetic susceptibility to Influenza A (H5N1) from family clustering data. Emerging Infectious Diseases 13(7): 1074-1076.
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Abstract: The apparent clustering of human cases of influenza A (H5N1) among blood relatives has been considered as evidence of genetic variation in susceptibility. We show that, by chance alone, a high proportion of clusters are expected to be limited to blood relatives when infection is a rare event.
Published Version: doi://10.3201/eid1307.061538
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878232/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:4551792
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