dc.contributor.author | Retsky, Michael W. | |
dc.contributor.author | Demicheli, Romano | |
dc.contributor.author | Hrushesky, William | |
dc.contributor.author | Speer, John | |
dc.contributor.author | Swartzendruber, Douglas | |
dc.contributor.author | Wardwell, Robert | |
dc.date.accessioned | 2010-11-16T14:44:13Z | |
dc.date.issued | 2004 | |
dc.identifier.citation | Retsky, Michael, Romano Demicheli, William Hrushesky, John Speer, Douglas Swartzendruber, and Robert Wardwell. 2005. Recent translational research: computational studies of breast cancer. Breast Cancer Research 7(1): 37-40. | en_US |
dc.identifier.issn | 1465-5411 | en_US |
dc.identifier.uri | http://nrs.harvard.edu/urn-3:HUL.InstRepos:4555853 | |
dc.description.abstract | The combination of mathematics – queen of sciences – and the general utility of computers has been used to make important inroads into insight-providing breast cancer research and clinical aids. These developments are in two broad areas. First, they provide useful prognostic guidelines for individual patients based on historic evidence. Second, by suggesting numeric tumor growth laws that are correlated to clinical parameters, they permit development of biologically relevant theories and comparison with patient data to help us understand complex biologic processes. These latter studies have produced many new ideas that are testable in clinical trials. In this review we discuss these developments from a clinical perspective, and ask whether and how they translate into useful tools for patient treatment. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | BioMed Central | en_US |
dc.relation.isversionof | doi://10.1186/bcr981 | en_US |
dc.relation.hasversion | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1064118/pdf/ | en_US |
dash.license | LAA | |
dc.subject | breast cancer | en_US |
dc.subject | computer models | en_US |
dc.subject | dormancy | en_US |
dc.subject | early detection | en_US |
dc.subject | exponential growth | en_US |
dc.subject | Gompertzian growth | en_US |
dc.subject | risk | en_US |
dc.title | Recent Translational Research: Computational Studies of Breast Cancer | en_US |
dc.type | Journal Article | en_US |
dc.description.version | Version of Record | en_US |
dc.relation.journal | Breast Cancer Research | en_US |
dash.depositing.author | Retsky, Michael W. | |
dc.date.available | 2010-11-16T14:44:13Z | |
dash.affiliation.other | SPH^Molecular+Integrative Physiological Sci Prog | en_US |
dc.identifier.doi | 10.1186/bcr981 | * |
dash.contributor.affiliated | Retsky, Michael | |