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dc.contributor.authorMueller, Nancy Elsa
dc.date.accessioned2010-11-22T14:52:56Z
dc.date.issued1995
dc.identifier.citationMueller, Nancy. 1995. Overview: viral agents and cancer. Environmental Health Perspectives 103(Suppl 8): 259-261.en_US
dc.identifier.issn0091-6765en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:4584623
dc.description.abstractSubstantial evidence indicates that several common viruses are clearly or probable causal factors in the etiology of specific malignancies. These viruses either normally establish latency or can become persistent infections. Oncogenesis is probably linked to an enhanced level of viral activation in the infected host, reflecting heavy viral dose or compromised immune control. The major virus-malignancy systems include hepatitis B virus (HBV), hepatitis C virus (HCV), and hepatocellular carcinoma; human lymphotropic virus-type 1 (HTLV-1) and adult T-cell leukemia/lymphoma (ATL); Epstein-Barr virus (EBV) and endemic Burkitt's lymphoma, nasopharyngeal carcinoma, and Hodgkin's disease; and human papilloma virus (HPV) and cervical cancer. Of these, a vaccine is available only for HBV. These malignancies tend to occur in early to mid-life and account for a substantial amount of morbidity and person-years lost. They are also likely to occur as "opportunistic malignancies" among individuals infected with human immunodeficiency virus type-1, particularly among those who experience prolonged survival.en_US
dc.language.isoen_USen_US
dc.publisherThe National Institute of Environmental Health Sciencesen_US
dc.relation.isversionofdoi:10.2307/3432322en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC1518960/pdf/en_US
dash.licenseLAA
dc.subjectvirusen_US
dc.subjectcanceren_US
dc.subjectHTLV-1en_US
dc.subjectHBVen_US
dc.subjectHCVen_US
dc.subjectEBVen_US
dc.subjectHPVen_US
dc.titleOverview: Viral Agents and Cancer.en_US
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden_US
dc.relation.journalEnvironmental Health Perspectivesen_US
dash.depositing.authorMueller, Nancy Elsa
dc.date.available2010-11-22T14:52:56Z
dash.affiliation.otherSPH^Epidemiologyen_US
dc.identifier.doi10.2307/3432322*
dash.contributor.affiliatedMueller, Nancy


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