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dc.contributor.authorPerdomo, Alejandro
dc.contributor.authorTruncik, Colin
dc.contributor.authorTubert-Brohman, Ivan
dc.contributor.authorRose, Geordie
dc.contributor.authorAspuru-Guzik, Alan
dc.date.accessioned2011-01-25T18:07:39Z
dc.date.issued2008
dc.identifier.citationPerdomo, Alejandro, Colin Truncik, Ivan Tubert-Brohman, Geordie Rose, and Alan Aspuru-Guzik. 2008. Construction of model Hamiltonians for adiabatic quantum computation and its application to finding low-energy conformations of lattice protein models. Physical Review A 78(1): 012320.en_US
dc.identifier.issn1050-2947en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:4685196
dc.description.abstractIn this paper we explore the use of a quantum optimization algorithm for obtaining low-energy conformations of protein models. We discuss mappings between protein models and optimization variables, which are in turn mapped to a system of coupled quantum bits. General strategies are given for constructing Hamiltonians to be used to solve optimization problems of physical, chemical, or biological interest via quantum computation by adiabatic evolution. As an example, we implement the Hamiltonian corresponding to the hydrophobic-polar model for protein folding. Furthermore, we present an approach to reduce the resulting Hamiltonian to two-body terms gearing toward an experimental realization.en_US
dc.description.sponsorshipChemistry and Chemical Biologyen_US
dc.language.isoen_USen_US
dc.publisherAmerican Physical Societyen_US
dc.relation.isversionofdoi: 10.1103/PhysRevA.78.012320en_US
dash.licenseOAP
dc.titleConstruction of Model Hamiltonians for Adiabatic Quantum Computation and its Application to Finding Low-Energy Conformations of Lattice Protein Modelsen_US
dc.typeJournal Articleen_US
dc.description.versionAccepted Manuscripten_US
dc.relation.journalPhysical Review Aen_US
dash.depositing.authorAspuru-Guzik, Alan
dc.date.available2011-01-25T18:07:39Z
dc.identifier.doi10.1103/PhysRevA.78.012320*
dash.contributor.affiliatedPerdomo, Alejandro
dash.contributor.affiliatedAspuru-Guzik, Alan


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