Grammatical Distinctions in the Left Frontal Cortex

DSpace/Manakin Repository

Grammatical Distinctions in the Left Frontal Cortex

Citable link to this page


Title: Grammatical Distinctions in the Left Frontal Cortex
Author: Shapiro, Kevin Alfred; Pascual-Leone, Alvaro; Mottaghy, Felix M.; Gangitano, Massimo; Caramazza, Alfonso

Note: Order does not necessarily reflect citation order of authors.

Citation: Shapiro, Kevin Alfred, Alvaro Pascual-Leone, Felix M. Mottaghy, Massimo Gangitano, and Alfonso Caramazza. 2001. Grammatical distinctions in the left frontal cortex. Journal of Cognitive Neuroscience 13(6): 713-720.
Full Text & Related Files:
Abstract: Selective deficits in producing verbs relative to nouns in speech are well documented in neuropsychology and have been associated with left hemisphere frontal cortical lesions resulting from stroke and other neurological disorders. The basis for these impairments is unresolved: Do they arise because of differences in the way grammatical categories of words are organized in the brain, or because of differences in the neural representation of actions and objects? We used repetitive transcranial magnetic stimulation (rTMS) to suppress the excitability of a portion of left prefrontal cortex and to assess its role in producing nouns and verbs. In one experiment subjects generated real words; in a second, they produced pseudowords as nouns or verbs. In both experiments, response latencies increased for verbs but were unaffected for nouns following rTMS. These results demonstrate that grammatical categories have a neuroanatomical basis and that the left prefrontal cortex is selectively engaged in processing verbs as grammatical objects.
Published Version: doi:10.1162/08989290152541386
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at
Citable link to this page:
Downloads of this work:

Show full Dublin Core record

This item appears in the following Collection(s)


Search DASH

Advanced Search