Show simple item record

dc.contributor.authorDay, Daniel Sindt
dc.contributor.authorLuquette, Lovelace j
dc.contributor.authorPark, Peter J.
dc.contributor.authorKharchenko, Peter Vasili
dc.date.accessioned2011-02-14T23:35:06Z
dc.date.issued2010
dc.identifier.citationDay, Daniel S., Lovelace J. Luquette, Peter J. Park, and Peter V. Kharchenko. 2010. Estimating enrichment of repetitive elements from high-throughput sequence data. Genome Biology 11(6): R69.en_US
dc.identifier.issn1465-6906en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:4725502
dc.description.abstractWe describe computational methods for analysis of repetitive elements from short-read sequencing data, and apply them to study histone modifications associated with the repetitive elements in human and mouse cells. Our results demonstrate that while accurate enrichment estimates can be obtained for individual repeat types and small sets of repeat instances, there are distinct combinatorial patterns of chromatin marks associated with major annotated repeat families, including H3K27me3/H3K9me3 differences among the endogenous retroviral element classes.en_US
dc.language.isoen_USen_US
dc.publisherBioMed Centralen_US
dc.relation.isversionofdoi:10.1186/gb-2010-11-6-r69en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911117/pdf/en_US
dash.licenseLAA
dc.titleEstimating Enrichment of Repetitive Elements from High-throughput Sequence Dataen_US
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden_US
dc.relation.journalGenome Biologyen_US
dash.depositing.authorLuquette, Lovelace j
dc.date.available2011-02-14T23:35:06Z
dash.affiliation.otherHMS^Center for Biomedical Informatics at Countwayen_US
dash.affiliation.otherHMS^Health Sciences and Technologyen_US
dash.affiliation.otherHMS^Pediatrics-Children's Hospitalen_US
dash.affiliation.otherHMS^Pediatrics-Children's Hospitalen_US
dc.identifier.doi10.1186/gb-2010-11-6-r69*
dash.contributor.affiliatedLuquette, Joe
dash.contributor.affiliatedPark, Peter
dash.contributor.affiliatedDay, Daniel
dash.contributor.affiliatedKharchenko, Peter


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record