A One-Step Synthesis of Pseudoephedrine Glycinamide, a Versatile Precursor for the Synthesis of a-Amino Acids

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A One-Step Synthesis of Pseudoephedrine Glycinamide, a Versatile Precursor for the Synthesis of a-Amino Acids

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Title: A One-Step Synthesis of Pseudoephedrine Glycinamide, a Versatile Precursor for the Synthesis of a-Amino Acids
Author: Gleason, James L.; Yoon, Taeyoung; Myers, Andrew G.

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Citation: Myers, Andrew G., Taeyoung Yoon, and James L. Gleason.
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Abstract: Both enantiomers of a pseudoephedrine glycinamide [(+)- or (-)-1] were synthesized by either of two procedures: (1) a standard two-step coupling of N-Boc-Gly with pseudoephedrine followed by deprotection, or (2) a more economical one-step coupling reaction of Gly-OMe with pseudoephedrine mediated by LiCl and base.
Published Version: http://dx.doi.org/10.1016/0040-4039(95)00820-3
Other Sources: http://www.chem.harvard.edu/groups/myers/pdf_publications/tetlet_1995_36_4555.pdf
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:4725866
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