dc.contributor.author | Carmeli, Yehuda | |
dc.contributor.author | Eliopoulos, George Miltiades | |
dc.contributor.author | Samore, Matthew H. | |
dc.date.accessioned | 2011-03-15T15:00:02Z | |
dc.date.issued | 2002 | |
dc.identifier.citation | Carmeli, Yehuda, George M. Eliopoulos, and Matthew H. Samore. 2002. Antecedent treatment with different antibiotic agents as a risk factor for vancomycin-resistant Enterococcus. Emerging Infectious Diseases 8(8): 802-807. | en_US |
dc.identifier.issn | 1080-6040 | en_US |
dc.identifier.uri | http://nrs.harvard.edu/urn-3:HUL.InstRepos:4741834 | |
dc.description.abstract | We conducted a matched case-control study to compare the effect of antecedent treatment with various antibiotics on subsequent isolation of vancomycin-resistant Enterococcus (VRE); 880 in-patients; 233 VRE cases, and 647 matched controls were included. After being matched for hospital location, calendar time, and duration of hospitalization, the following variables predicted VRE positivity: main admitting diagnosis; a coexisting condition (e.g., diabetes mellitus, organ transplant, or hepatobiliary disease); and infection or colonization with methicillin-resistant Staphylococcus aureus or Clostridium difficile within the past year (independent of vancomycin treatment). After controlling for these variables, we examined the effect of various antibiotics. Intravenous treatment with third-generation cephalosporins, metronidazole, and fluoroquinolones was positively associated with VRE. In our institution, when we adjusted the data for temporo-spatial factors, patient characteristics, and hospital events, treatment with third-generation cephalosporins, metronidazole, and fluoroquinolones was identified as a risk factor for VRE. Vancomycin was not a risk factor for isolation of VRE. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | Centers for Disease Control and Prevention | en_US |
dc.relation.isversionof | doi:10.3201/eid0808.010418 | en_US |
dc.relation.hasversion | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732508/pdf/ | en_US |
dash.license | LAA | |
dc.title | Antecedent Treatment with Different Antibiotic Agents as a Risk Factor for Vancomycin-Resistant Enterococcus | en_US |
dc.type | Journal Article | en_US |
dc.description.version | Version of Record | en_US |
dc.relation.journal | Emerging Infectious Diseases | en_US |
dash.depositing.author | Carmeli, Yehuda | |
dc.date.available | 2011-03-15T15:00:02Z | |
dash.affiliation.other | HMS^Medicine- Beth Israel-Deaconess | en_US |
dc.identifier.doi | 10.3201/eid0808.010418 | * |
dash.contributor.affiliated | Eliopoulos, George | |
dash.contributor.affiliated | Carmeli, Yehuda | |