Cytological profiling: providing more haystacks for chemists' needles
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CitationLorang, Janet and Randall W. King. 2005. Cytological profiling: providing more haystacks for chemists' needles. Genome Biology 6(8): 228.
AbstractConventional high-throughput ‘chemical genetic’ screening seeks to identify small-molecule
inhibitors of a specific protein or pathway. A recent study describes how unbiased screening of
cellular morphology, followed by affinity purification to identify targets of compounds with
interesting effects, can lead to the identification of novel inhibitors.
Citable link to this pagehttp://nrs.harvard.edu/urn-3:HUL.InstRepos:4743815
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