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dc.contributor.authorLee, Joonyeol
dc.contributor.authorMaunsell, John
dc.date.accessioned2011-03-18T18:11:52Z
dc.date.issued2009
dc.identifier.citationLee, Joonyeol, and John H. R. Maunsell. 2009. A normalization model of attentional modulation of single unit responses. PLoS ONE 4(2): e4651.en_US
dc.identifier.issn1932-6203en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:4744854
dc.description.abstractAlthough many studies have shown that attention to a stimulus can enhance the responses of individual cortical sensory neurons, little is known about how attention accomplishes this change in response. Here, we propose that attention-based changes in neuronal responses depend on the same response normalization mechanism that adjusts sensory responses whenever multiple stimuli are present. We have implemented a model of attention that assumes that attention works only through this normalization mechanism, and show that it can replicate key effects of attention. The model successfully explains how attention changes the gain of responses to individual stimuli and also why modulation by attention is more robust and not a simple gain change when multiple stimuli are present inside a neuron's receptive field. Additionally, the model accounts well for physiological data that measure separately attentional modulation and sensory normalization of the responses of individual neurons in area MT in visual cortex. The proposal that attention works through a normalization mechanism sheds new light a broad range of observations on how attention alters the representation of sensory information in cerebral cortex.en_US
dc.language.isoen_USen_US
dc.publisherPublic Library of Scienceen_US
dc.relation.isversionofdoi:10.1371/journal.pone.0004651en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC2645695/pdf/en_US
dash.licenseLAA
dc.titleA Normalization Model of Attentional Modulation of Single Unit Responsesen_US
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden_US
dc.relation.journalPLoS ONEen_US
dash.depositing.authorMaunsell, John
dc.date.available2011-03-18T18:11:52Z
dash.affiliation.otherHMS^Neurobiologyen_US
dc.identifier.doi10.1371/journal.pone.0004651*
dash.contributor.affiliatedMaunsell, John H. R.


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