Imaging of the unstable plaque: how far have we got?

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Imaging of the unstable plaque: how far have we got?

Show simple item record Matter, Christian M. Stuber, Matthias Nahrendorf, Matthias 2011-04-07T20:30:29Z 2009
dc.identifier.citation Matter, Christian M., Matthias Stuber, and Matthias Nahrendorf. 2009. Imaging of the unstable plaque: how far have we got?. European Heart Journal 30(21): 2566-2574. en_US
dc.identifier.issn 0195-668X en_US
dc.identifier.issn 1522-9645 en_US
dc.description.abstract Rupture of unstable plaques may lead to myocardial infarction or stroke and is the leading cause of morbidity and mortality in western countries. Thus, there is a clear need for identifying these vulnerable plaques before the rupture occurs. Atherosclerotic plaques are a challenging imaging target as they are small and move rapidly, especially in the coronary tree. Many of the currently available imaging tools for clinical use still provide minimal information about the biological characteristics of plaques, because they are limited with respect to spatial and temporal resolution. Moreover, many of these imaging tools are invasive. The new generation of imaging modalities such as magnetic resonance imaging, nuclear imaging such as positron emission tomography and single photon emission computed tomography, computed tomography, fluorescence imaging, intravascular ultrasound, and optical coherence tomography offer opportunities to overcome some of these limitations. This review discusses the potential of these techniques for imaging the unstable plaque. en_US
dc.language.iso en_US en_US
dc.publisher Oxford University Press en_US
dc.relation.isversionof doi://10.1093/eurheartj/ehp419 en_US
dc.relation.hasversion en_US
dash.license LAA
dc.subject Atherosclerosis en_US
dc.subject Molecular imaging en_US
dc.subject Vulnerable plaque en_US
dc.title Imaging of the unstable plaque: how far have we got? en_US
dc.type Journal Article en_US
dc.description.version Version of Record en_US
dc.relation.journal European Heart Journal en_US Nahrendorf, Matthias 2011-04-07T20:30:29Z
dash.affiliation.other HMS^Radiology-Massachusetts General Hospital en_US

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