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dc.contributor.authorMatter, Christian M.
dc.contributor.authorStuber, Matthias
dc.contributor.authorNahrendorf, Matthias
dc.date.accessioned2011-04-07T20:30:29Z
dc.date.issued2009
dc.identifier.citationMatter, Christian M., Matthias Stuber, and Matthias Nahrendorf. 2009. Imaging of the unstable plaque: how far have we got?. European Heart Journal 30(21): 2566-2574.en_US
dc.identifier.issn0195-668Xen_US
dc.identifier.issn1522-9645en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:4815536
dc.description.abstractRupture of unstable plaques may lead to myocardial infarction or stroke and is the leading cause of morbidity and mortality in western countries. Thus, there is a clear need for identifying these vulnerable plaques before the rupture occurs. Atherosclerotic plaques are a challenging imaging target as they are small and move rapidly, especially in the coronary tree. Many of the currently available imaging tools for clinical use still provide minimal information about the biological characteristics of plaques, because they are limited with respect to spatial and temporal resolution. Moreover, many of these imaging tools are invasive. The new generation of imaging modalities such as magnetic resonance imaging, nuclear imaging such as positron emission tomography and single photon emission computed tomography, computed tomography, fluorescence imaging, intravascular ultrasound, and optical coherence tomography offer opportunities to overcome some of these limitations. This review discusses the potential of these techniques for imaging the unstable plaque.en_US
dc.language.isoen_USen_US
dc.publisherOxford University Pressen_US
dc.relation.isversionofdoi://10.1093/eurheartj/ehp419en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771148/pdf/en_US
dash.licenseLAA
dc.subjectAtherosclerosisen_US
dc.subjectMolecular imagingen_US
dc.subjectVulnerable plaqueen_US
dc.titleImaging of the unstable plaque: how far have we got?en_US
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden_US
dc.relation.journalEuropean Heart Journalen_US
dash.depositing.authorNahrendorf, Matthias
dc.date.available2011-04-07T20:30:29Z
dash.affiliation.otherHMS^Radiology-Massachusetts General Hospitalen_US
dc.identifier.doi10.1093/eurheartj/ehp419*
dash.contributor.affiliatedNahrendorf, Matthias


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