Altered Metabolism in Cancer
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CitationLocasale, Jason W., and Lewis C. Cantley. 2010. Altered metabolism in cancer. BMC Biology 8: 88.
AbstractCancer cells have different metabolic requirements from their normal counterparts. Understanding the consequences of this differential metabolism requires a detailed understanding of glucose metabolism and its relation to energy production in cancer cells. A recent study in BMC Systems Biology by Vasquez et al. developed a mathematical model to assess some features of this altered metabolism. Here, we take a broader look at the regulation of energy metabolism in cancer cells, considering their anabolic as well as catabolic needs. See research article: http://www.biomedcentral.com/1752-0509/4/58/
Citable link to this pagehttp://nrs.harvard.edu/urn-3:HUL.InstRepos:4817633
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