A Mouse Plasma Peptide Atlas as a Resource for Disease Proteomics

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A Mouse Plasma Peptide Atlas as a Resource for Disease Proteomics

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Title: A Mouse Plasma Peptide Atlas as a Resource for Disease Proteomics
Author: Menon, Rajasree; Deutsch, Eric W; Pitteri, Sharon J; Faca, Vitor M; Newcomb, Lisa F; Bardeesy, Nabeel; Hung, Kenneth E; Jacks, Tyler; Politi, Katerina; Aebersold, Ruedi; Omenn, Gilbert S; States, David J; Hanash, Samir M; Zhang, Qing; Wang, Hong; DePinho, Ronald A.; Dinulescu, Daniela M; Kucherlapati, Raju

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Citation: Zhang, Qing, Rajasree Menon, Eric W. Deutsch, Sharon J. Pitteri, Vitor M. Faca, Hong Wang, Lisa F. Newcomb, et al. 2008. A mouse plasma peptide atlas as a resource for disease proteomics. Genome Biology 9(6): R93.
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Abstract: We present an in-depth analysis of mouse plasma leading to the development of a publicly available repository composed of 568 liquid chromatography-tandem mass spectrometry runs. A total of 13,779 distinct peptides have been identified with high confidence. The corresponding approximately 3,000 proteins are estimated to span a 7 logarithmic range of abundance in plasma. A major finding from this study is the identification of novel isoforms and transcript variants not previously predicted from genome analysis.
Published Version: doi:10.1186/gb-2008-9-6-r93
Other Sources: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481425/pdf/
Terms of Use: This article is made available under the terms and conditions applicable to Other Posted Material, as set forth at http://nrs.harvard.edu/urn-3:HUL.InstRepos:dash.current.terms-of-use#LAA
Citable link to this page: http://nrs.harvard.edu/urn-3:HUL.InstRepos:4866217
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