Depressive symptoms and glycemic control in adolescents with type 1 diabetes

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Depressive symptoms and glycemic control in adolescents with type 1 diabetes

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dc.contributor.author McGrady, Meghan E.
dc.contributor.author Drotar, Dennis
dc.contributor.author Repaske, David
dc.contributor.author Hood, Korey K.
dc.contributor.author Laffel, Lori Michelle Burtz
dc.date.accessioned 2011-04-23T03:59:44Z
dc.date.issued 2009
dc.identifier.citation McGrady, Meghan E., Lori Laffel, Dennis Drotar, David Repaske, and Korey K. Hood. 2009. Depressive symptoms and glycemic control in adolescents with type 1 diabetes. Diabetes Care 32(5): 804-806. en_US
dc.identifier.issn 0149-5992 en_US
dc.identifier.uri http://nrs.harvard.edu/urn-3:HUL.InstRepos:4874780
dc.description.abstract OBJECTIVE—To determine whether the association between depressive symptoms and glycemic control is mediated by blood glucose monitoring (BGM). RESEARCH DESIGN AND METHODS—A total of 276 adolescents with type 1 diabetes (mean age ± SD, 15.6 ± 1.4 years) completed a measure of depressive symptoms. Sociodemographic and family characteristics were obtained from caregivers. BGM frequency and glycemic control were obtained at a clinic visit. RESULTS—Separate regression analyses revealed that depressive symptoms were associated with lower BGM frequency (B = −0.03; P = 0.04) and higher A1C (B = 0.03; P = 0.05) and that lower BGM frequency was associated with higher A1C (B = −0.39; P < 0.001). With depressive symptoms and BGM frequency included together, only BGM frequency was associated with A1C and depressive symptoms became nonsignificant (B = 0.02; P = 0.19). The Sobel test was significant (Z = 1.96; P < 0.05) and showed that 38% of the depression-A1C link can be explained by BGM. CONCLUSIONS—BGM is a mediator between depressive symptoms and glycemic control in adolescents with type 1 diabetes. en_US
dc.language.iso en_US en_US
dc.publisher American Diabetes Association en_US
dc.relation.isversionof doi:10.2337/dc08-2111 en_US
dc.relation.hasversion http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671131/pdf/ en_US
dash.license LAA
dc.subject clinical care en_US
dc.subject education en_US
dc.subject nutrition en_US
dc.subject psychosocial research en_US
dc.title Depressive symptoms and glycemic control in adolescents with type 1 diabetes en_US
dc.type Journal Article en_US
dc.description.version Version of Record en_US
dc.relation.journal Diabetes Care en_US
dash.depositing.author Laffel, Lori Michelle Burtz
dc.date.available 2011-04-23T03:59:44Z
dash.affiliation.other HMS^Pediatrics-Children's Hospital en_US

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