Open source model for generating RR intervals in atrial fibrillation and beyond

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Open source model for generating RR intervals in atrial fibrillation and beyond

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dc.contributor.author Lian, Jie
dc.contributor.author Müssig, Dirk
dc.contributor.author Lang, Volker
dc.contributor.author Clifford, Gari D
dc.date.accessioned 2011-04-26T00:57:56Z
dc.date.issued 2007
dc.identifier.citation Lian, Jie, Gari D. Clifford, Dirk Müssig, and Volker Lang. 2007. Open source model for generating RR intervals in atrial fibrillation and beyond. BioMedical Engineering OnLine 6: 9. en_US
dc.identifier.issn 1475-925X en_US
dc.identifier.uri http://nrs.harvard.edu/urn-3:HUL.InstRepos:4875878
dc.description.abstract Background: Realistic modeling of cardiac inter-beat (RR) intervals is highly desirable for basic research in cardiac electrophysiology, clinical management of heart diseases, and developing signal processing tools for ECG analysis. Methods: We present an open source computer model that is capable to generate realistic time series of RR intervals in both physiologic and pathologic conditions. Detailed model structure and the software implementation are described. Results: Examples are provided on how to use this model to generate RR intervals in atrial fibrillation with ventricular pacing, normal sinus rhythm with heart rate variability, and typical atrial flutter with atrioventricular block. The extensibility of the model is also discussed. Conclusion: The present computer model provides a unified platform wherein various types of ventricular rhythm can be simulated. The availability of this open source model promises to support and stimulate future studies. en_US
dc.language.iso en_US en_US
dc.publisher BioMed Central en_US
dc.relation.isversionof doi:10.1186/1475-925X-6-9 en_US
dc.relation.hasversion http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1820785/pdf/ en_US
dash.license LAA
dc.title Open source model for generating RR intervals in atrial fibrillation and beyond en_US
dc.type Journal Article en_US
dc.description.version Version of Record en_US
dc.relation.journal BioMedical Engineering OnLine en_US
dash.depositing.author Clifford, Gari D
dc.date.available 2011-04-26T00:57:56Z
dash.affiliation.other HMS^Medicine-Brigham and Women's Hospital en_US

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