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dc.contributor.authorWright, Rosalind Jo
dc.date.accessioned2011-04-28T05:37:55Z
dc.date.issued2008
dc.identifier.citationWright, Rosalind J. 2008. Stress and childhood asthma risk: overlapping evidence from animal studies and epidemiologic research. Allergy, Asthma, and Clinical Immunology 4(1): 29-36.en_US
dc.identifier.issn1710-1484en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:4878932
dc.description.abstractRapidly expanding evidence increasingly strengthens the evidence linking psychological factors to asthma and allergy expression. Parallel studies in animals and humans demonstrating the influence of prenatal maternal stress and early caregiving experiences on the disrupted regulation of defensive biological systems [eg, sympathetic and adrenomedullary (SAM) system and the hypothalamicpituitary-adrenocortical (HPA) axis] provide strong proof of concept for this line of research. The consequent altered neuroimmune responses may influence the expression of immune-mediated disorders such as asthma as well as enhance an individual's susceptibility to other environmental factors that may also contribute to asthma risk.en_US
dc.language.isoen_USen_US
dc.publisherBioMed Centralen_US
dc.relation.isversionofdoi:10.1186/1710-1492-4-1-29en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC2869338/pdf/en_US
dash.licenseLAA
dc.subjectasthmaen_US
dc.subjectchildhooden_US
dc.subjectinteractionsen_US
dc.subjectprenatalen_US
dc.subjectstressen_US
dc.titleStress and childhood asthma risk: overlapping evidence from animal studies and epidemiologic researchen_US
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden_US
dc.relation.journalAllergy, Asthma, and Clinical Immunologyen_US
dash.depositing.authorWright, Rosalind Jo
dc.date.available2011-04-28T05:37:55Z
dash.affiliation.otherHMS^Medicine-Brigham and Women's Hospitalen_US
dash.affiliation.otherSPH^Environmental+Occupational Medicine+Epien_US
dc.identifier.doi10.1186/1710-1492-4-1-29*
dash.contributor.affiliatedWright, Rosalind Jo


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