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dc.contributor.authorBatacchi, Stefano
dc.contributor.authorMatano, Stefania
dc.contributor.authorNella, Alessandra
dc.contributor.authorZagli, Giovanni
dc.contributor.authorBonizzoli, Manuela
dc.contributor.authorPasquini, Andrea
dc.contributor.authorAnichini, Valentina
dc.contributor.authorTucci, Valentina
dc.contributor.authorManca, Giuseppe
dc.contributor.authorValeri, Andrea
dc.contributor.authorPeris, Adriano
dc.contributor.authorBan, Kevin M.
dc.date.accessioned2011-04-28T06:34:48Z
dc.date.issued2009
dc.identifier.citationBatacchi, Stefano, Stefania Matano, Alessandra Nella, Giovanni Zagli, Manuela Bonizzoli, Andrea Pasquini, Valentina Anichini, et al. 2009. Vacuum-assisted closure device enhances recovery of critically ill patients following emergency surgical procedures. Critical Care 13(6): R194.en_US
dc.identifier.issn1364-8535en_US
dc.identifier.urihttp://nrs.harvard.edu/urn-3:HUL.InstRepos:4878942
dc.description.abstractIntroduction: Critically ill surgical patients frequently develop intra-abdominal hypertension (IAH) leading to abdominal compartment syndrome (ACS) with subsequent high mortality. We compared two temporary abdominal closure systems (Bogota bag and vacuum-assisted closure (VAC) device) in intra-abdominal pressure (IAP) control. Methods: This prospective study with a historical control included 66 patients admitted to a medical and surgical intensive care unit (ICU) of a tertiary care referral center (Careggi Hospital, Florence, Italy) from January 2006 to April 2009. The control group included patients consecutively treated with the Bogota bag (Jan 2006-Oct 2007), whereas the prospective group was comprised of patients treated with a VAC. All patients underwent abdominal decompressive surgery. Groups were compared based upon their IAP, SOFA score, serial arterial lactates, the duration of having their abdomen open, the need for mechanical ventilation (MV) along with length of ICU and hospital stay and mortality. Data were collected from the time of abdominal decompression until the end of pressure monitoring. Results: The Bogota and VAC groups were similar with regards to demography, admission diagnosis, severity of illness, and IAH grading. The VAC system was more effective in controlling IAP (P < 0.01) and normalizing serum lactates (P < 0.001) as compared to the Bogota bag during the first 24 hours after surgical decompression. There was no significant difference between the SOFA scores. When compared to the Bogota, the VAC group had a faster abdominal closure time (4.4 vs 6.6 days, P = 0.025), shorter duration of MV (7.1 vs 9.9 days, P = 0.039), decreased ICU length of stay (LOS) (13.3 vs 19.2 days, P = 0.024) and hospital LOS (28.5 vs 34.9 days; P = 0.019). Mortality rate did not differ significantly between the two groups. Conclusions: Patients with abdominal compartment syndrome who were treated with VAC decompression had a faster abdominal closure rate and earlier discharge from the ICU as compared to similar patients treated with the Bogota bag.en_US
dc.language.isoen_USen_US
dc.publisherBioMed Centralen_US
dc.relation.isversionofdoi:10.1186/cc8193en_US
dc.relation.hasversionhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811940/pdf/en_US
dash.licenseLAA
dc.titleVacuum-assisted closure device enhances recovery of critically ill patients following emergency surgical proceduresen_US
dc.typeJournal Articleen_US
dc.description.versionVersion of Recorden_US
dc.relation.journalCritical Careen_US
dash.depositing.authorBan, Kevin M.
dc.date.available2011-04-28T06:34:48Z
dash.affiliation.otherHMS^Medicine- Beth Israel-Deaconessen_US
dc.identifier.doi10.1186/cc8193*
dash.authorsorderedfalse
dash.contributor.affiliatedBan, Kevin M.


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