Browsing FAS Theses and Dissertations by Title
Now showing items 1070-1089 of 6136
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Defuse the News: Predicting Misinformation and Bias in News on Social Networks via Content-Blind Learning
(2018-06-29)As the locus of social discourse shifts to the Internet, information travels faster than ever before. Consequently, the risks to truth are high when misinformation propagates through social networks billions of individuals ... -
Degenerations, Log K3 Pairs and Low Genus Curves on Algebraic Varieties
(2016-04-28)We investigate several questions pertaining to the enumerative and deformation-theoretic behavior of low-genus curves on algebraic varieties, using specialization techniques. -
Deletion of an exhaustion-specific PD-1 enhancer modulates CD8+ T cell fate and function
(2022-09-06)Exhaustion is a state of CD8+ T cell dysfunction arising during chronic viral infection and cancer. Exhausted T cells are less proliferative and less cytotoxic, produce less cytokine, and express high levels of co-inhibitory ... -
Delineating genome alterations in cancer with long-read and linked-read sequencing
(2023-06-01)Cancer is driven by alterations to the genome. The continued invention and application of new methods has gradually enhanced our ability to characterize of genome alterations in cancer with much greater scale and resolution. ... -
Delineating HIV-1 Evolutionary Pathways in an Individual With a Broadly Neutralizing Antibody Response
(2020-09-08)Despite the identification of potent broadly neutralizing antibodies (bNAbs) against HIV-1, such as VRC01 and VRC13, the induction of bNAbs through vaccination remains hindered due to an incomplete understanding of the ... -
Delivering Across Boundaries: Social and Structural Features of Service Integration
(2018-05-14)The ability to integrate services across settings and time is increasingly important for healthcare delivery organizations. This dissertation explores the organizational structures and social behaviors that enable service ... -
Delivering the Lotus-Born: Historiography in the Tibetan Renaissance
(2013-02-19)Traditionally recognized as the first of the great Buddhist treasure revealers, Nyang-rel Nyima Özer (1124-1192) historiographically reconstructed the Imperium into a golden age of Tibetan Buddhism. An analysis of his two ... -
Delivering the Right Amount of Care – Sometimes Less Is More
(2017-05-15)New technologies utilized in clinical practice offer improved tools for diagnosing and treating patients. In some cases, these improvements cause unintended consequences by leading to the diagnosis of indolent or otherwise ... -
Demand for Redistribution in the Age of Inequality
(2014-10-21)This dissertation investigates the dynamics of mass attitudes toward redistributive social policies in post-industrial democracies: How have these attitudes changed over time? What factors and mechanisms drive these changes? ... -
Democracy and the University: America and the Reconstruction of German Higher Education, 1945-1966
(2023-06-01)This dissertation explores the intellectual and practical debates over the role of the university in a democratic society by examining the reconstruction and reorientation of German universities in the aftermath of the ... -
Democracy Beyond Disclosure: Secrecy, Transparency, and the Logic of Self-Government
(2017-01-19)"Transparency" is the constant refrain of democratic politics, a promised aid to accountability and integrity in public life. Secrecy is stigmatized as a work of corruption, tolerable (if at all) by a compromise of democratic ... -
Democratic Equality in the Misinformation Age
(2022-11-23)Conventional wisdom blames the “epistemic crisis” of American politics on the leveling force of social media and the collapse of traditional gatekeepers. This dissertation argues democracy’s vulnerability to misinformation ... -
Democratic Performances: How Theater Creates the People
(2023-06-01)This work offers the concept of “democratic performance” as a corollary of “people’s theater.” “People’s theater” is a branch of the performing arts that aims to engage a particular audience, which is made of new spectators, ... -
Democratic Theory and the Question of Character
(2013-02-12)This dissertation uses the history of political thought to shed light on the disconnect between the prominent place of judgments about the character in American democratic life, and the marginalized place of those judgments ... -
Democratizing Money: A Political Theory of Policymaking
(2022-06-06)Political theorists have long wrestled with the appropriate role for experts in democracy. Several recent popular movements have sought to reject expert rule by promising to “take back control” or “topple neoliberal elites.” ... -
Demonic (Dis)Possessions: Indigenous Gold from the Colombia-Panama Borderlands
(2024-03-12)This dissertation takes a long view at the marginalization in archaeological models of pre-Conquest metallurgy from northern Chocó and Urabá in the Colombia-Panama borderlands. It was here, where Europeans found—in the ... -
Dendrite Patterning as a Model for Self-Organizing Systems
(2018-01-05)Biological systems self-organize into complex well-ordered structures and can evolve new patterns when perturbed. To identify principles underlying self-organization, I turned to the model organism C. elegans for its ... -
Dendritic branch structure compartmentalizes calcium-dependent plasticity signals and supports the acquisition of complex tuning functions
(2022-05-12)Life as an organism depends on flexible and intelligent neural activity for perceiving the sensory world, constructing models of the environment, and generating adaptive behaviors. It is evident that the collective activity ... -
Denotational Translation Validation
(2013-01-02)In this dissertation we present a simple and scalable system for validating the correctness of low-level program transformations. Proving that program transformations are correct is crucial to the development of security ... -
Density-Based Separations in Aqueous Multiphase Systems: Tools for Biological Research and Low-Cost Diagnostics
(2014-06-06)Cells often exist in heterogeneous mixtures. Density provides a property to separate several types of cells from the mixed sample in which they originate. Density-based separation methods provide a standard method to ...