Browsing FAS Theses and Dissertations by Title
Now showing items 205-224 of 6136
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Algorithms for Political Methodology in the Information Age
(2024-03-12)Contemporary politics is bound to an unprecedented volume of online information, and to the algorithms and social networks that deliver it. From millions of online campaign ads to billions of fake news social media posts, ... -
Algorithms for the People: Democracy in the Age of AI
(2022-06-06)Our society is being transformed by prediction tools like artificial intelligence and machine learning. And yet, we find ourselves chasing tech companies whose AI systems we know nothing about, condemning algorithms that ... -
Algorithms for Voting and Group Selection
(2023-09-07)Many of the core challenges in social choice, new and old, stand to benefit from consideration through the computational lens. We demonstrate the particular applicability of approximation algorithms to the tasks of aggregating ... -
All Above: Visual Culture and the Professionalization of City Planning, 1867-1931
(2013-02-11)This dissertation is developed around questions of how cultural fascinations with seeing the city from above are intertwined with the birth and development of the city planning profession. To explore this question, I examine ... -
All Features Great and Small: Distinguishing the effects of specific magnetically active features on radial-velocity exoplanet detections
(2021-08-23)State of the art radial velocity (RV) exoplanet searches are limited by the effects of stellar magnetic activity. Magnetically active features, such as spots, plage, and network regions, each contribute to the observed RV ... -
All for One, Pre-K for All: Assessing the Impact of Universal Pre-Kindergarten on Single Mothers in New York City
(2021-06-17)In the 2014-2015 school year, New York City implemented a universal pre-kindergarten program called “Pre-K for All” open to all four-year-old children. This paper uses triple-difference economic methodology and personal ... -
"All May Na Man Have in Talle": The Parabiblical Imaginary in Medieval English Literature
(2016-09-16)This is a study of four fourteenth-century narrative poems written in a parabiblical mode. The poems—Cursor Mundi (c. 1300), Cleanness, Patience and Pearl (all c. 1380s)—are substantially and thematically concerned with ... -
All-Optical Neurophysiology in the 1-Photon Regime
(2018-05-13)Simultaneous optical recording and optical stimulation of neuronal activity could enable faster and more comprehensive investigation of neuronal function but is hampered by underdeveloped tools. Pairs of molecular transducers ... -
Allele-specific detection of single mRNA molecules in situ and the study of transcriptional regulation
(2014-10-21)We developed a method for fluorescence in situ identification of individual mRNA molecules, allowing quantitative and accurate measurement, in single cells, of allele-specific transcripts that differ by only a few nucleotides. ... -
Allele-Specific Gene Expression in the Laboratory Mouse
(2013-02-07)Traditionally, autosomal genes, when expressed, are assumed to express both alleles equally. Exceptions to this tenet include genes for which a specific genotypic polymorphism controls expression level, as well as genes ... -
Allelic imbalance of chromatin accessibility in cancer identifies candidate causal risk variants and their mechanisms
(2022-09-07)Understanding the functional impact of non-coding variants remains a major challenge in cancer genetics. In the case of non-coding germline risk associations from GWAS, many associations are in high LD and cannot be resolved ... -
Allosteric Integrase Inhibitors Reveal a Role for Integrase During HIV-1 Maturation
(2015-09-20)Integration of the DNA copy of the HIV-1 genome is an essential step for virus replication and is mediated by a homotetrameric complex of the viral protein integrase (IN) in association with the ends of linear viral DNA ... -
Allowing Spontaneity: Practice, Theory, and Ethical Cultivation in Longchenpa's Great Perfection Philosophy of Action
(2018-05-11)This is a study of the philosophy of practical action in the Great Perfection poetry and spiritual exercises of the fourteenth century Tibetan author, Longchen Rabjampa Drime Ozer (klong chen rab 'byams pa dri med 'od zer ... -
Almost the Same but Not Quite - the Prosthetic Condition in Latin American Artistic Practices
(2018-09-25)My dissertation studies works of art that simultaneously feature literary and visual components, and that were produced in Latin America after 1980. To approach them, I propose the notion of the prosthetic condition: a way ... -
The ALS-Linked Gene TDP-43 Regulates \(IFN\beta\) Expression through a Novel Mechanism of 3' UTR-Mediated Promoter cis-Regulation
(2013-03-20)The TAR DNA-binding protein (TDP-43) is a heterogeneous nuclear ribonucleprotein that is involved in multiple stages of RNA processing. Mutations in the TDP-43 gene and mislocalization of TDP-43 protein have been implicated ... -
Alterations in Energy Metabolism and Neurodegeneration as a Conseqeunce of DNA Damage
(2017-01-18)The correlation between DNA damage and aging has been discussed since Peter Medawar framed the first modern theory of aging in 1952. In support of a causal relationship between DNA damage and aging, most human segmental ... -
Alternate Compactifications of Hurwitz Spaces
(2012-12-19)We construct several modular compactifications of the Hurwitz space \(H^d_{g/h}\) of genus g curves expressed as d-sheeted, simply branched covers of genus h curves. They are obtained by allowing the branch points of the ... -
Alternate structures regulate transcription and translation of RNA viral genomes
(2022-06-06)With the emergence of new RNA-structure related techniques, it is becoming increasingly clear that viral RNA genomes are structurally and functionally plastic, which drive multiple phases of the viral lifecycle. My doctoral ... -
Alternating selection for dispersal and multicellularity favors regulated life cycles
(2023-05-02)The evolution of complex multicellularity opened paths to increased morphological diversity and organizational novelty. This transition involved three processes: cells remained attached to one another to form groups, cells ... -
Alternative Histories of the White Cube: European Modernism and Mediterranean Vernacular
(2022-04-13)This dissertation investigates historical formulations of the white cube as a link between European modernism and Mediterranean vernacular. Architectural history consistently presents white and cubical modernist designs ...