Browsing FAS Theses and Dissertations by Title
Now showing items 1111-1130 of 6136
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Design of Wearable Robots for the Hip and Knee for Gait Assistance with Selective Mechanical Transparency
(2022-03-17)In recent years, research on wearable assistive devices has shown increasing promise for enhancing human mobility. However, several barriers remain to widespread adoption of these devices for practical real-world use. The ... -
Design Optimization and Immune Kinetics of mRNA Vaccines
(2022-05-16)mRNA vaccines allow for rapid development and large-scale production, making them prime candidates for infectious disease outbreak response. CVnCoV (CureVac) is an mRNA vaccine developed to mitigate the current pandemic ... -
Design Principles for Improving Precision and Dexterity of Soft Robotic Hands
(2022-01-05)As robots move more and more into the real world, they need to be equipped to interact with a wide array of objects and environment features while maintaining a gentle touch. Soft robotic end effectors enable passive ... -
Design, Dynamics, and Energetics of a Meso-Scale Flapping-Wing Robot
(2018-08-31)Biological fliers are capable of extremely agile and efficient flight. Man-made flapping-wing micro air vehicles (FWMAVs) on the scale of insects and small birds have been used to understand and mimic the behaviors of their ... -
Design, Manufacturing, and Locomotion Studies of Ambulatory Micro-Robots
(2013-09-27)Biological research over the past several decades has elucidated some of the mechanisms behind highly mobile, efficient, and robust locomotion in insects such as the cockroach. Roboticists have used this information to ... -
Design, Synthesis, and Application of a Rapidly Diversifiable Trioxacarcin Pharmacophore in Antibody-Drug Conjugates
(2023-03-23)The trioxacarcin natural products are structurally complex, densely oxygenated bacterial isolates with exquisite biological activity towards a number of different human cancer cell lines. Following an initial isolation ... -
Designing and Probing Open Quantum Systems: Quantum Annealing, Excitonic Energy Transfer, and Nonlinear Fluorescence Spectroscopy
(2012-07-27)The 20th century saw the first revolution of quantum mechanics, setting the rules for our understanding of light, matter, and their interaction. The 21st century is focused on using these quantum mechanical laws to develop ... -
Designing Datalog-Based Embedded Languages
(2023-06-30)Datalog is a declarative, domain-specific programming language grounded in principles of logic. At its essence, it expresses computation on relational data in a manner that is both understandable by humans and easy for ... -
Designing Novel Semiconductor Nanowire Structures: Synthesis and Fabrication for Localized Photodetection and Sensing
(2015-05-06)Semiconductor nanowires display a wide range of structural and functional diversity, and as such provide a platform for nanomaterials research. At present, a number of nanowire structural motifs have been discovered and ... -
Designing Scalable Biological Interfaces
(2014-06-06)This thesis presents the analysis and design of biological interfacing technologies in light of a need for radical improvements in scalability. It focuses primarily on structural and functional neural data acquisition, but ... -
Designing singularities in electronic dispersions
(2018-09-16)This dissertation is devoted to the study of singularities in electronic dispersions and their implications for electronic systems. First, we consider two-dimensional interacting electrons at a monkey saddle with dispersion ... -
Designing Viscoelastic Bioelectronic Interfaces: From the Organ to Cell Scale
(2022-06-06)Living tissues are non-linearly elastic materials that exhibit viscoelasticity and plasticity. Man-made, implantable bioelectronic arrays mainly rely on thin films of ductile metals encapsulated by rigid plastic or hydrophobic ... -
Desiring Athletes: The Meaning of Athletic Imagery on Red-Figure Athenian Symposium Pottery
(2023-09-05)This dissertation explores the iconography of athletes on Athenian red-figure pottery of the late sixth and fifth centuries BCE, a period in which athletic imagery pervaded the homes, marketplaces, and sanctuaries of ancient ... -
The Destabilizing Effects of ETFs and Options on Underlying Stock Returns
(2015-06-26)This paper explores the role that ETFs and options have on the underlying stock return. Using a dataset of 400 stocks over a five year period, I examine the effect that ETF rebalancing and option hedging have on stock ... -
Detecting -1 Programmed Ribosomal Frameshifting in Bacterial Genomes: A Probabilistic Approach
(2022-06-03)Programmed ribosomal frameshifting (PRF or frameshift) is a phenomenon that allows the same RNA sequence to code for two different peptides. In short, the presence of a 7 nucleotide (base) "slippery" motif in the mRNA ... -
Detecting Meaningful Relationships in Large Data Sets
(2018-05-01)As data sets grow and algorithms scale, two questions have become central to data-rich science. The first is the exploration question: how can we avoid only testing hypotheses consistent with current models and instead ... -
Detecting Single Photons with Graphene-Based Josephson Junctions
(2020-11-23)In this work I present theory, modeling, and experimentation demonstrating that the graphene-based Josephson junction (GJJ) is a capable system for the detection of single photons across the electromagnetic spectrum, from ... -
Detecting System Anomalies Using Kernel-level Data Provenance
(2022-05-11)Modern cyber-attacks are increasingly difficult to detect. For example, advanced persistent threats (APTs) slowly infiltrate a network of systems and can remain undetected for months. Alternatively, attackers can corrupt ... -
Detection and Characterization of Autism Spectrum Disorder and Parkinson’s Disease Utilizing Measures of Speech- and Fine-Motor Coordination
(2023-05-02)Neurological disorders such as Autism Spectrum Disorder (ASD) and Parkinson’s Disease (PD) are typically associated with observed motor difficulties in speech production and in fine-motor tasks (including oculo-motor tasks), ... -
Detection of Single-Molecule Optical Absorption at Room Temperature and Mechanistic Study of Transcriptional Bursting
(2014-06-06)Advances in optical imaging techniques have allowed quantitative studies of many biological systems. This dissertation elaborates on our efforts in both developing novel imaging modalities based on detection of optical ...