Browsing FAS Theses and Dissertations by Title
Now showing items 2797-2816 of 6097
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In Search of Truth: Jealousy and the Violation of Privacy in Marcel Proust
(2021-06-23)Marcel Proust’s In Search of Lost Time is, among many other things, a landmark study of jealousy. Proust depicts two sides to jealousy: The Proustian lover exemplifies the internal and imaginative, even aesthetic, side of ... -
In Sickness and in Health: Americans and Psychiatry in Korea, 1950-1962
(2014-06-06)This dissertation begins with a simple set of questions: how and why did the Western discipline of psychiatry gain traction in the Republic of Korea? My answers point to the Korean War and the US-ROK alliance as the two ... -
In situ epigenomics across length scales
(2022-09-09)Chromatin is spatially organized across length scales, from DNA base pairs to chromosomes to tissues. This organization, which is encompassed in the term epigenomics, is thought to regulate gene expression and control ... -
In the City, Out of Place: Dispossession and the Economics of Belonging in Southeastern Turkey
(2013-08-21)This dissertation analyzes everyday talk about livelihoods, or about the challenges of work and getting by, among displaced Kurds in the city of Diyarbakır in southeastern Turkey. Over the past two decades, Diyarbakır has ... -
In the Epicenter: Surveilling, Supporting, and Punishing Families amid the Rural Opioid Crisis and Beyond
(2021-11-16)While the opioid crisis has impacted communities across the United States, it has left a particularly indelible mark on Central Appalachia—an area widely regarded as the “epicenter” of the crisis. One consequence has been ... -
In the Guise of Holiness: Sanctity and Portraiture in the Early Modern Hispanic World
(2016-05-16)This dissertation examines the intersection of sacred and profane imagery in Spanish territories, including Spain, New Spain, and Naples, between 1520 and 1700. In particular, it focuses on so-called sanctified portraits, ... -
In the wake of Boko Haram’s Terror: A Study of Internal Displacement in Northeast Nigeria
(2023-09-12)This dissertation investigates internal displacement caused by Boko Haram’s violent extremism and insurgency in Nigeria’s northeastern state of Borno. Specifically, I examine how new social and economic structures, that ... -
In vitro models of the segmentation clock reveal metabolic regulation of developmental rate
(2022-06-06)How species-specific rates of development are set represents a major unanswered question in developmental biology. This gap in our knowledge stems in large part from a lack of simple assays to precisely measure developmental ... -
In Vitro Studies of Amyotrophic Lateral Sclerosis Using Human Pluripotent Stem Cell-Derived Motor Neurons
(2015-05-14)Among the disciplines of medicine, the study of neurological disorders such as amyotrophic lateral sclerosis (ALS) is particularly challenging. In ALS, both cortical and spinal motor neurons progressively degenerate, leading ... -
In vitro Studies of Myofibers and Their Use in Analyzing the Differential Dynamics and Properties of α-Actinin Isoforms
(2014-06-06)Skeletal muscle is a highly organized tissue that requires cooperation of many different structures and components for proper function. We explored the use of a flexor digitorum brevis (FDB) myofiber culture system to ... -
In Vivo and in Vitro Characterization of the Tumor Suppressive Function of INPP4B
(2015-05-16)The phosphatases PTEN and INPP4B are frequently deregulated in human cancer and have been proposed to act as tumor suppressor genes by coordinately antagonizing PI3K/AKT signaling. While the function of PTEN has been ... -
In Vivo Delivery of Precision Genome Editing Agents
(2023-03-14)The capabilities of researchers to modify the mammalian genome has expanded greatly in the last decade, but translation of these editing technologies to therapeutics is limited by the lack of efficient means to deliver the ... -
In Vivo Genetic Screening to Identify Mechanisms of Resistance to Cancer Immunotherapy
(2017-10-10)Despite the dramatic clinical success of cancer immunotherapy with PD-1 checkpoint blockade, most patients do not experience sustained clinical benefit from treatment, suggesting that additional therapeutic strategies are ... -
In Vivo Reprogramming of Neuronal Identity and Local Connectivity in the Neocortex
(2017-01-20)Neurons of the mammalian central nervous system are widely considered as canonical examples of terminally differentiated cells. Using excitatory projection neurons (PNs) of the mouse neocortex as a model, this dissertation ... -
In/voluntary Attachments: Marriage, Caste, and Gender in Tamil Nadu
(2023-05-11)This dissertation examines the relationship between voluntariness, marital kinship, and the production of caste and gender stratification in contemporary Tamil Nadu. Over the last decade, ‘inter-caste marriages’ between ... -
Incentive-Aware Machine Learning for Decision Making
(2022-08-12)Machine Learning algorithms are increasingly being deployed in consequential decision-making for people's lives. These decisions affect widely different aspects of our lives; e.g., Machine Learning algorithms decide what ... -
Incentives Design in the Presence of Externalities
(2015-09-23)The design of incentives becomes challenging when faced with externalities. In this thesis I resolve this difficulty in two settings: position auctions and software economies. The first part of the thesis studies value ... -
Incentives for War in Small-Scale Societies
(2015-04-30)This dissertation investigates why men in small-scale societies participate in warfare. The answer to this question has implications for understanding the role of war in our species’ history, as well as the evolution of ... -
Income Risk and Aggregate Demand over the Business Cycle
(2012-07-23)This dissertation consists of three essays on income risk and aggregate demand over the business cycle, each addressing an aspect of the Great Recession. The first chapter reframes the standard liquidity trap model to ... -
Incorporating Haydn’s Minuets: Towards a Somatic Theory of Music
(2015-09-29)This dissertation addresses a repertoire and an issue that have both been somewhat neglected in musicological studies—the minuets of Joseph Haydn, and the somatic experience of dance. Of all Haydn’s compositions, his minuets ...