Browsing FAS Theses and Dissertations by Title
Now showing items 1-20 of 5859
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1,2-Selective Hydrosilylation of Conjugated Dienes
(2014-06-06)Selective 1,2-hydrosilylation of 1,3-dienes is a challenging problem to solve for transition metal catalysis. Butadiene, specifically, would be a useful substrate because 3-butenylsilane products have promise as superior ... -
The 1824 Confederation of the Equator and Cultural Production in Brazil
(2015-05-17)During the 1824 Confederation of the Equator revolt in northeastern Brazil, a middle-class junta rose to power and waged a war against the monarchy in Rio, journalists participating in creating pedagogical ideological ... -
2-Selmer groups and Heegner points on elliptic curves
(2015-05-07)This thesis studies several aspects of the arithmetic of elliptic curves. In particular, we explore the prediction of the Birch and Swinnerton-Dyer conjecture when the 2-Selmer group has rank one. For certain elliptic ... -
2d String Theory and the Non-Perturbative c=1 Matrix Model
(2020-05-15)A valuable testing ground for exploring new features of string theory and quantum gravity is the duality between c=1 string theory and the c=1 matrix quantum mechanics, which has been explored for over 30 years. In this ... -
3D Bioprinting of Vascularized Human Tissues
(2016-04-26)The ability to manufacture human tissues that replicate the spatial, mechano-chemical, and temporal aspects of biological tissues would enable myriad applications, including drug screening, disease modeling, and tissue ... -
3D Printing of Liquid Crystal Elastomer Actuators
(2021-07-12)Soft robotics offer advantages over their rigid counterparts due to the intrinsic softness of their consisting materials, soft robotic matter. When equipped with programmable shape morphing and controllable function, soft ... -
4d Spectra from BPS Quiver Dualities
(2013-09-26)We attack the question of BPS occupancy in a wide class of 4d N = 2 quantum field theories. We first review the Seiberg-Witten approach to finding the low energy Wilsonian effective action actions of such theories. In ... -
“‘A Bath of Continuous Sensations’: Warren Brodey’s Quest for Human Augmentation and Intelligent Environments, 1955-1975”
(2018-05-13)This dissertation traces the professional and intellectual development of Warren Brodey (b. 1924). Trained as a psychiatrist and psychoanalyst, Brodey was one of the pioneers of family therapy but eventually abandoned his ... -
A Capitalizing City: Dar Es Salaam and the Emergence of an African Entrepreneurial Elite (C. 1862-2015)
(2018-09-19)A Capitalizing City charts the ways some people of African descent in Dar es Salaam, the commercial and industrial capital of Tanzania, have attempted, historically, to either integrate into the modern capitalist system ... -
A Chemical Biology Approach Towards Targeting Understudied Lipid Kinases in Cancer and Ebola
(2019-05-18)Cellular processes are orchestrated in an intricate and highly coordinated fashion in order to facilitate proper metabolism, cell cycle progression, gene expression, and ultimately survival. Phosphoinositides, lipid moieties ... -
A Chemical Biology Platform to Develop Small Molecule Probes for Bromodomains
(2017-05-16)Bromodomain epigenetic reader proteins play crucial roles in the pathogenesis of diseases ranging from inflammation to cancer. Small molecule inihibitors have engendered a nuanced understanding of the role of BET subfamily ... -
A Chemical Odor Map in Cortex
(2017-09-08)Odorous molecules trigger specific percepts. Appropriate assignment of odorants to corresponding percepts relies on the brain’s ability to both discriminate distinct odorants, as well as generalize odorants that share ... -
A Classy Affair: Modeling Course Enrollment Prediction
(2020-06-18)The problem of course enrollment prediction has many implications in the determination of university policy. Namely, logistic concerns around course planning cause many universities, Harvard among them, to consider moving ... -
A Clock-Phased Sigma Factor Cascade Is Required for Global Circadian Transcriptional Rhythms in Cyanobacteria
(2017-09-07)The circadian clock of the cyanobacterium Synechococcus elongatus PCC 7942 drives oscillations in global mRNA transcript abundances with 24 h periodicity under continuous light conditions. The transcription factor RpaA ... -
A Coherence of Incoherences: Graeco-Arabic Philosophy and the Fifteenth-Century Ottoman Synthesis of Philosophy With Sharia
(2019-09-11)The fifteenth-century Ottoman world was a dynamic seedbed of philosophical and theological debates and was particularly marked by numerous adjudications produced by certain celebrated scholars who synthesized different ... -
A combinatorial view of canonical Wnt signaling
(2020-05-15)This computational thesis is concerned with two problems, one methodological, the other scientific. The scientific problem consists in understanding the behavior of the canonical Wnt signaling pathway at a molecular systems ... -
A Computational Approach to Analysis and Control\\of the Mammalian Circadian Oscillator
(2018-05-11)Circadian rhythms, endogenous, entrainable, near-24 h oscillations in metabolism, are a nearly ubiquitous feature of life on Earth. Circadian rhythms function as a feedforward biological control system that reorganizes ... -
A Constellation of Outposts: French Intelligence Services and the Administration of the French Protectorate of Morocco, 1912-1937
(2018-09-25)This dissertation examines the metastasis of the French colonial intelligence state. It argues that rogue intelligence officers hijacked power in the French Protectorate of Morocco and created a covert regime to evade ... -
A Continuum Model of Cell Fate in the Response of Human Cells to Ionizing Radiation
(2017-09-08)In response to ionizing radiation induced DNA damage, human cells can either recover and resume proliferation or activate anti-proliferative programs such as cell death and cellular senescence, a state characterized by the ... -
A Convectively-Coupled Framework for Understanding Hurricane Azimuthal Asymmetries and Secondary Eyewall Formation
(2020-05-14)Tropical cyclones (TCs) or hurricanes are among the most devastating natural disasters. Improvement of intensity forecasts of hurricanes is not yet satisfactory. Among all the factors that can influence the intensity of a ...