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Roles of the multifunctional protein Spn1 in transcription and chromatin biology
(2020-01-22)
Gene transcription by RNA polymerase II (RNAPII) is a tightly regulated process necessary for the development and growth of all eukaryotes. In addition to synthesizing RNA, RNAPII coordinates—through a variety of ...
Introduction of Polycomb‐mediated Compaction and Phase Separation Activity in Stem Cells Impairs Differentiation
(2020-04-30)
In multicellular organisms, the Polycomb group (PcG) proteins play a significant role in maintaining the repression of specific target genes across development. There are five proteins in the mammalian Cbx family that can ...