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Free Actin and Effects on Lung Macrophage Bacterial Defenses
Actin release into the circulation and extracellular space, with subsequent removal by the actin scavenging protein plasma gelsolin (pGSN), has long been reported in injury and infection. Our laboratory’s recent finding ...
Clp-Mediated Regulation of the Mycobacterial Cell Cycle
Tuberculosis is currently the most deadly infectious disease worldwide. Given the high rates of treatment failure, new antibiotics are desperately needed. Antibacterial drugs typically target DNA replication, cell growth, ...