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Fitness Tradeoffs, Bimodality, and the Genetics of Natural Variation in Glucose-Galactose Sensing Across Saccharomyces Cerevisiae
In nature, cells must constantly sense their environment and respond appropriately. These cellular “decisions” are implemented by molecular components that can mutate and evolve. How do mutations lead to changes in cellular ...
Genetic Engineering Toward a 57-Codon Genome
Scientific progress in fundamental biology has drastically transformed our ability to engineer biological systems, with diverse applications in medicine and industry, from insulin and artemisin production in prokaryotes ...
Cyanobacteria and Friends: Engineered Photosynthetic Microbial Communities
Microbial communities are the rule rather than the exception. Laboratories using model organisms often focus on monoclonal, axenic cultures overlooking the importance of the interactions, division of labor, and robustness ...