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Modeling Rare Protein-Coding Variation to Identify Mutation-Intolerant Genes With Application to Disease 

Samocha, Kaitlin E. (2016-05-06)
Sequencing exomes—the 1% of the genome that codes for proteins—has increased the rate at which the genetic basis of a patient’s disease is determined. Unfortunately, when a patient does not carry a well-established pathogenic ...
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Molecular Patterns and Signatures of Longevity 

Ma, Siming (2016-05-02)
Since their divergence from a common ancestor some 200 million years ago, mammals have undergone significant diversification in physiology, morphology, habitat, size, and longevity. The maximum lifespan of mammalian species ...

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  • Ma, Siming (1)
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  • Medical Sciences$:$ (2)
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  • 2016$:$ (2)

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