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Integrated Stimuli-Responsive Functionalities: From Bioseparation to Dynamic Optics 

Shastri, Ankita (2016-05-04)
Nature demonstrates the efficiency of hierarchically integrated components that work in cooperation to produce a variety of useful phenomena in organisms, such as movement or shape change. A key feature of these components ...
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Reactivity and Selectivity in Aryl C–H Functionalization by Electrophilic Radicals 

Boursalian, Gregory Bagrad (2016-05-04)
Two main challenges hinder the development of new, broadly useful C–H functionalization reactions: (1) most C–H bonds constitute part of the relatively inert backbone of an organic molecule, so it is difficult to elicit ...
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Sol-Gel Chemistry of Inverse Opals 

Phillips, Katherine Reece (2016-04-28)
Controlling nano to microscale structuration enables one to alter a material’s optical, wetting, mechanical, and chemical properties. Structuration on this scale can be formed from spherical building blocks; in particular, ...
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A New Active Cell Culture Material for Controlled Cell Micro-Manipulation 

Sutton, Amy (2016-05-14)
Mechanical forces in the cell’s natural environment have a crucial impact on growth and behavior, from single-cell gene expression and cell division to the spatial patterning of complex organ architectures. Few areas of ...
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The Development of a Cell-Based Screen for Discovering Lipopolysaccharide Biogenesis Inhibitors 

Zhang, Ge (2018-09-16)
Gram-negative bacteria are more difficult to kill than Gram-positive bacteria due to the presence of an outer membrane that prevents many antibiotics from reaching their cellular targets. The outer membrane is an asymmetric ...
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Evolution of Diversely Functionalized Nucleic Acid Polymers 

Chen, Zhen (2018-04-19)
Darwinian evolution gave rise to biopolymers with a myriad of folded structures and functions, as well as all the diverse life forms on earth that are supported by those molecules. Amazingly, the essence of molecular ...
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Peptide-Assisted Nonenzymatic RNA Replication in Coacervate Droplets 

Jia, Tony Z. (2016-09-14)
Life on earth may have first appeared in the form of a protocell capable of metabolism and containing a self-replicating informational polymer. This polymer was likely to have been RNA due to its ability to serve both as ...
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Development of Small Molecule Kinase Degraders as Chemical Biology Probes and Cancer Therapies 

Dobrovolsky, Dennis (2018-09-20)
Advances in chemical biology provide immense benefits to human health through the discovery of new medicines and new scientific tools to study disease. I have contributed to the advancement of this field by developing a ...
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Chemical Approaches to the Surface Engineering of Paper and Cellulose-Based Materials for Microfluidics, Electronics and Low-Cost Diagnostics 

Glavan, Ana (2016-01-27)
Paper (and other cellulose-based materials such as cotton thread and fabrics) are underexploited as materials for the construction of “high-tech” and “lab-on-a-chip” devices. One major drawback of paper is its tendency to ...
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Novel nanowire structures and devices for nanoelectronic bioprobes 

Jiang, Zhe (2015-04-29)
Semiconductor nanowire materials and devices provide unique opportunities in the frontier between nanoelectronics and biology. The bottom-up paradigm enables flexible synthesis and patterning of nanoscale building blocks ...
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