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Re-Engineering the Tumor Microenvironment to Enhance Drug Delivery
(2013-02-22)
Tumors are similar to organs, with unique physiology giving rise to an unusual set of transport barriers to drug delivery. Cancer therapy is limited by non-uniform drug delivery via blood vessels, inhomogeneous drug transport ...
The Connection between Microphysical Morphology and Atmospheric Particle Phase Transitions
(2013-02-11)
The phase of atmospheric particles can influence heterogeneous chemistry, cloud formation, and radiative forcing. Sulfate particles ranging from sulfuric acid to ammonium sulfate are the largest contributor arising from ...
Face Identification in the Internet Era
(2013-02-11)
Despite decades of effort in academia and industry, it is not yet possible to build machines that can replicate many seemingly-basic human perceptual abilities. This work focuses on the problem of face identification that ...
Magnetic Spheres in Viscous Flows and at Interfaces: Sorting, Coating, and Interfacial Deformation
(2013-02-11)
Magnetic microparticles are often used in laboratory settings for the separation of biological material. These microparticles can also be useful in microfluidic settings because of their small size and the possibility of ...
Integrated Optofluidic Multimaterial Fibers
(2013-02-11)
The creation of integrated microphotonic devices requires a challenging assembly of optically and electrically disparate materials into complex geometries with nanometer-scale precision. These challenges are typically ...
Small Interfering RNA Imaging Probes for Neurological Applications
(2013-03-19)
Small interfering RNAs (siRNAs) have emerged as a potent new class of therapeutics that regulate gene expression through sequence-specific inhibition of mRNA translation. Clinical trials of siRNAs have highlighted the need ...
Nanoscale Magnetic Imaging with a Single Nitrogen-Vacancy Center in Diamond
(2013-03-18)
Magnetic imaging has been playing central roles not only in fundamental sciences but also in engineering and industry. Their numerous applications can be found in various areas, ranging from chemical analysis and biomedical ...
Reducing Power Loss, Cost and Complexity of SoC Power Delivery Using Integrated 3-Level Voltage Regulators
(2013-03-18)
Traditional methods of system-on-chip (SoC) power management based on dynamic voltage and frequency scaling (DVFS) is limited by 1) cores/IP blocks sharing a voltage domain provided by off-chip voltage regulators (VR) and ...
Inferring Speaker Affect in Spoken Natural Language Communication
(2013-03-15)
The field of spoken language processing is concerned with creating computer programs that can understand human speech and produce human-like speech. Regarding the problem of understanding human speech, there is currently ...
Defects in Hard-Sphere Colloidal Crystals
(2013-03-15)
Colloidal crystals of \(1.55 \mu m\) diameter silica particles were grown on {100} and flat templates by sedimentation and centrifugation. The particles interact as hard spheres. The vacancies and divacancies in these ...