Randomized experiments are the gold standard for inferring causal effects of treatments. However, complications often arise in randomized experiments when trying to incorporate additional information that is observed after ...

Core-collapse supernovae (SNe) are the highly energetic explosions of massive stars (> 8 solar masses) that are pervasive in their influence throughout astrophysics. They are the phenomenon with primary responsibility for ...

This thesis consists of results relating to the theoretical and computational advances in modeling the Normal-Normal hierarchical model.

Factorial designs have been widely used in many scientific and industrial settings, where it is important to distinguish "active'' or real factorial effects from "inactive" or noise factorial effects used to estimate ...

A relatively recent increase in the popularity of evidence-based activism has created a higher demand for statisticians to work on human rights and economic development projects. The statistical challenges of revealing ...

Since the completion of the sequencing of the human genome at the turn of the century, genomics has revolutionized the study of biology and medicine by providing high-throughput and quantitative methods for measuring ...

The goal of this dissertation was to examine the realized value of targeted therapies in routine care and to identify opportunities for improving the return on medical spending for these technologies. Chapter 1 investigated ...

We examine three topics related to experimental design in this dissertation. Two are related to the analysis of experimental data and the other focuses on the design of paired comparison experiments, in this case knockout ...

How to properly aggregate indirect information is more and more important. In this dissertation, we will present two aspects of the issue: indirect comparison of treatment effects and aggregation of ordered-based rank data.

Studies with stratified cluster designs, called complex surveys, have increased in popularity in medical research recently. With the passing of the Affordable Care Act, more information about effectiveness of treatment, ...