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Semiparametric Methods for Causal Mediation Analysis and Measurement Error
(2015-08-06)
Chapter 1: Since the early 2000s, evidence has accumulated for a significant differential effect of first-line antiretroviral therapy (ART) regimens on human immunodeficiency virus (HIV) treatment outcomes, such as CD4 ...
Improving Reproductive Health: Assessing Determinants and Measuring Policy Impacts
(2016-05-11)
In this thesis, I investigate policies and programs to improve reproductive health. My thesis makes a substantive contribution to reproductive health policy and a methodological contribution to quasi-experimental research. ...
On the Statistical Properties of Epidemics on Networks
(2016-05-09)
One major aim of statistics is to systematically study outcomes of interest in a population by observing the properties of a sample of that population. Some outcomes, such as the total number of people infected in an ...
Physician Preferences for Medical Innovation
(2018-05-15)
Health care spending growth challenges the budgets of governments, businesses, and families. In 2015, one in every six dollars spent in the U.S. economy was related to health care – twice the share in 1980. The rapid growth ...
Evaluating Health Interventions Over Time: Empirical Tests of the Validity of the Single Interrupted Time Series Design
(2016-08-29)
Single interrupted time series (ITS) is a quasi-experimental evaluation design used frequently in the health policy literature. This manuscript investigates the validity of single ITS through two within-study comparisons ...
Policy and Methods in Health Services Research
(2016-09-13)
This dissertation consists of two policy papers and one methods paper, all grounded in applied, empirical health-services research. The first two papers concern the influence of medical underwriting in the market for ...
Statistical Methods for Estimating the Effects of Multi-Pollutant Exposures in Children's Health Research
(2016-09-15)
We develop statistical strategies to explore how time-varying exposures to heavy metal mixtures affects cognition and cognitive trajectories in children. In chapter 1, we develop a Bayesian model, called Lagged Kernel ...
Quantitative Methods for Stratified Medicine
(2015-05-15)
Stratified medicine has tremendous potential to deliver more effective therapeutic intervention to improve public health. For practical implementation, reliable prediction models and clinically meaningful categorization ...