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In search of breast cancer cell secretions with therapeutic and diagnostic value.
(2014-06-06)
The first end point of this study was to identify specific pro-apoptotic or anti-proliferative factors in the breast cancer cell secretome. To this end, we designed an in vitro screen that effectively cross-cultured 20 ...
Serum and Glucocorticoid-Regulated Kinase Signaling in Breast Cancer
(2014-02-25)
Oncogenic activating mutations in PIK3CA, the gene encoding the catalytic subunit of phosphoinositide 3-kinase (PI 3-K), are highly prevalent in breast cancer. The protein kinase Akt is considered to be the primary effector ...