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Structure-Function Analysis of the Conserved Histone Chaperone Spt6
(2014-06-06)
Chromatin structure is crucial to regulate access to the genome for processes such as a transcription, recombination, DNA repair, and DNA replication. Spt6, a key factor involved in regulating chromatin structure, is ...
Characterization of nucleosome occupancy in mammalian cells
(2014-10-21)
Chromatin is a complex of genomic DNA, RNA, and associated proteins. Many of the processes that occur on chromatin regulate the accessibility of the genetic material of a cell. The nucleosome is the basic subunit of ...