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Activation and Antagonism of RIG-I-Mediated Innate Immune Signaling by Herpes Simplex Virus 1
The cytosolic innate immune receptor retinoic acid-inducible gene-I (RIG-I) recognizes double-stranded RNA (dsRNA) that emerges during viral infection and initiates an antiviral response comprised of interferon (IFN) and ...
Functional analysis of multiple activities associated with the herpes simplex virus-1 DNA polymerase
Of the DNA replication proteins required for herpes simplex virus-1 (HSV-1) viral replication, the catalytic subunit of the DNA polymerase (Pol) has been the most extensively studied, both as a model for Family B polymerases ...