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The processes mediating capsid trafficking during human cytomegalovirus nuclear egress
(2017-05-11)
Herpesviruses are widespread pathogens that cause or contribute to an array of human diseases. Viral DNA synthesis, capsid assembly, and packaging occur in nucleoplasmic structures called replication compartments (RCs), ...
Structural and Functional Characterization of Viral Membrane Proteins by Solution NMR Spectroscopy
(2017-01-25)
Viral membrane proteins play an integral role in the viral life cycle and are targets for antiviral drugs and vaccine design. Despite their importance, very little is known about the structure and function of this class ...
Cutaneous Papillomavirus E6 Inhibit NOTCH and TGF-Beta Signaling to Disrupt Keratinocyte Differentiation.
(2017-01-19)
Cutaneous beta-papillomaviruses are associated with non-melanoma skin cancers that arise in patients who suffer from a rare genetic disorder, Epidermodysplasia Verruciformis or after immunosuppression following organ ...