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Biophysical Studies of the Lpt Pathway
(2017-07-06)
The outer membrane (OM) of Gram-negative bacteria is impermeable to many antibiotics because its outer leaflet is composed entirely of lipopolysaccharide (LPS), a large glycolipid with an extracellular saccharide that is ...
Phage Assisted Evolutions for Engineering Biosynthetic Pathways
(2018-05-14)
Phage Assisted Continuous Evolution (PACE) and its derivative techniques are powerful tools for evolving improved and altered enzymatic activities. Prior to this work, no one had demonstrated the applicability of these ...