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Topics in Causal Inference and the Law
(2018-04-13)
Randomized experiments are a fundamental tool for estimating the causal effects of proposed interventions. While analysis of some experiments can be quite straightforward, other experiments may present difficult analytical ...
Katherine Cohen Senior Thesis
(2018-06-29)
The viral dynamics model based on a system of differential equations is an incredibly useful tool towards understanding the kinetics of HIV. The parameters of the system of equations provide important insights into the ...
Inference for Incomplete Data and Dependent Data
(2018-05-15)
This thesis is about statistical inference on two classes of data: incomplete data (Chapters 1, 2 and 3) and dependent data (Chapter 4). Chapter 2 relaxes one crucial assumption made in Chapter 1, and then Chapter 3 further ...
Global Signatures of Selection in Humans
(2018-05-13)
This thesis studies the properties and prevalence of natural selection operating on our species on a global or genome-wide scale. It is still not known how negative selection against deleterious mutations operates genome-wide, ...
The Yoga of Dying: Xuanzang on the Nature of Death
(2018-05-15)
This study reclaims the investigation undertaken by Xuanzang (602-667 C.E.) 玄奘, the translator and peripatetic scholar-monk of the Tang Dynasty, and his translation team, into the nature of dying. It conforms to the ...
Repair, Restoration, and Reintegration Following Work-Related Failures
(2018-09-06)
It is almost inevitable that some organizational members will fall short of meeting important organizational standards, and organizations often have explicit procedures for disciplining employees after such violations. ...
Probabilistic Models of Structure in Biological Sequences
(2018-09-25)
The machinery of life is encoded in biological polymers for which sequence, structure, and function are intimately connected. This dissertation presents new probabilistic models for uncovering these connections from ...
Mapping the Relationship Between Interstellar Dust and Radiation in the Milky Way
(2018-05-15)
We present a simple but effective technique for measuring angular variation in R_V across the sky. We divide stars from the Pan-STARRS catalog into Healpix pixels and determine the posterior distribution of reddening and ...
Fatigue of Hydrogels
(2018-04-19)
Hydrogels are actively studied and developed in both fundamental understanding and modern applications. Traditional hydrogels are soft and brittle. Hydrogels with toughness and stiffness comparable to natural rubber have ...
Targeting FGFR to Overcome EMT-Related Resistance to EGFR Inhibition in EGFR-Mutated Non-Small Cell Lung Cancer
(2018-01-19)
Acquired drug resistance to tyrosine kinase inhibitor (TKI) targeted therapies remains a major clinical challenge. In EGFR mutant non-small cell lung cancer (NSCLC), therapeutic failure of EGFR TKIs can result from both ...