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Pointing to On-Point Answers: An Approach for Query-Based Biomedical Summarization
(2018-06-29)
In my thesis, I explored the potential of deep learning for query-based biomedical summarization. Summary questions from the BioASQ Dataset, derived from PubMed research abstracts, pose challenges for deep learning-based ...
The Dynamics of a "Selfish Mining" Infested Bitcoin Network: How the Presence of Adversaries Can Alter the Profitability Framework of Bitcoin Mining
(2018-06-29)
Bitcoin mining is a process that serves to both verify sets of transactions and slowly introduce new currency into the system. As a reward for performing this process, miners are paid in bitcoin for the blocks they mine. ...
Almost the Same but Not Quite - the Prosthetic Condition in Latin American Artistic Practices
(2018-09-25)
My dissertation studies works of art that simultaneously feature literary and visual components, and that were produced in Latin America after 1980. To approach them, I propose the notion of the prosthetic condition: a way ...
STING Engages Distinct Antiviral Mechanisms to Restrict RNA Virus and DNA Virus Replication
(2018-01-19)
In mammalian cells, interferon (IFN) responses that occur during RNA and DNA virus infections are activated by distinct signaling pathways. The RIG-I-like-receptors (RLR) bind viral RNA and engage the adaptor MAVS to promote ...
Epigenetic Alterations Induced by Human Papillomavirus E6 and E7 Oncoproteins
(2018-05-11)
High-risk human papillomaviruses (HPVs) account for over 99 percent of cervical carcinomas as well as other anogenital tract and oropharyngeal carcinomas. The E6 and E7 oncoproteins are consistently expressed in cervical ...
VSV Vectors as Vaccines for Emerging Viruses and as Probes for Entry Pathways
(2018-05-12)
Viral fusion proteins (VFPs) are membrane-anchored machines that coat the surfaces of enveloped viruses and induce the fusion of virus and cell membranes. While enveloped viruses are evolutionarily diverse, their fusion ...
Molecular phylogeny of the wood-boring beetle family Buprestidae and insights into the evolution of host use
(2018-05-13)
The family Buprestidae, also known as jewel beetles or metallic wood-boring beetles, contains nearly 15,000 species in 522 genera. Together with the small family Schizopodidae (7 species, 3 genera), they form the superfamily ...
Development of Small Molecule Kinase Degraders as Chemical Biology Probes and Cancer Therapies
(2018-09-20)
Advances in chemical biology provide immense benefits to human health through the discovery of new medicines and new scientific tools to study disease. I have contributed to the advancement of this field by developing a ...
Thesis 1: Quantum Algorithm for Handling Missing Data, Thesis 2: Simulation Method for Open Quantum Systems
(2018-06-29)
Thesis 1: In the last few years, we have seen significant progress in the quantum computing field. What seemed distant is now becoming a reality. Therefore, an important task in this field is to find applications where a ...
Variations on a Nilpotence Theorem of Hopkins and Mahowald
(2018-05-08)
It is a theorem of Hopkins and Mahowald that the nilpotence of $p$-torsion classes in $\mathbb{E}_2$-ring spectra can be detected by the classical $H\mathbb{F}_p$-Hurewicz homomorphism. On the other hand, the May Nilpotence ...