Now showing items 151-156 of 156
Programming molecular behavior: development and applications of autonomous DNA synthesis cascades
DNA serves many functional roles in living organisms, and dynamic DNA nanotechnology seeks to expand this set of DNA-based behaviors through the rational design of new functions. In the past 20 years, the predictable and ...
Studies of the Laboulbeniomycetes: Diversity, Evolution, and Patterns of Speciation
CHAPTER 1: Laboulbeniales is one of the most morphologically and ecologically distinct orders of Ascomycota. These microscopic fungi are characterized by an ectoparasitic lifestyle on arthropods, determinate growth, lack ...
Flagellar Biosynthesis in E.coli Is Regulated by a Cascade of Stochastic Pulses
Genetically identical populations of bacteria can exhibit significant phenotypic heterogeneity even in the absence of environmental variations. In bacteria such as Bacillus and Salmonella, flagellar motility has been found ...
Elucidating Influences of Substrate DNA Sequences on AID Targeting and Outcome During Antibody Maturation
During antibody maturation, Activation Induced Cytidine Deaminase (AID) initiates antibody variable (V) exon somatic hypermutation (SHM) for affinity maturation in germinal centers (GCs) and IgH switch (S) region DNA breaks ...
Alterations in Energy Metabolism and Neurodegeneration as a Conseqeunce of DNA Damage
The correlation between DNA damage and aging has been discussed since Peter Medawar framed the first modern theory of aging in 1952. In support of a causal relationship between DNA damage and aging, most human segmental ...
Optimizing Nanodiscs for Membrane Proteins and Mapping a Translation Initiation Complex
Nanodiscs have been an excellent tool for encouraging biochemists and structural biologists to study membrane proteins. They are composed of a discoidal lipid bilayer and two copies of a membrane scaffold protein (MSP). ...