Now showing items 11-20 of 617
Non-Enzymatic Copying of Nucleic Acid Templates
All known living cells contain a complex set of molecular machinery to support their growth and replication. However, the earliest cells must have been much simpler, consisting of a compartment and a genetic material to ...
Particle Focusing in Microchannels
The ability to control the motion of particles and cells in microchannels has been a center of fascination since the advent of microfluidics. Entire fields have been created in order to accomplish separation, volume reduction ...
Beyond the Modern Beauty: Takehisa Yumeji and the New Media Environment in Early Twentieth Century Japan
This thesis focuses on the modern Japanese artist Takehisa Yumeji (1884-1934) and his diverse range of graphic production, from illustrations in socialist newspapers and magazines with images of anti-war and leftist sentiment ...
Essays in International Trade and Development
This dissertation studies different aspects of the interaction between developed and developing countries in global supply chains. The first chapter studies the matching between importing and exporting firms in global ...
Cellular and Systemic Metabolic Adaptations to Energy Status
My thesis work has focused on physiological adaptations to nutrient stress; from genes, environment and hormonal perspective, and how failure of these systems result in common chronic diseases.
Control of Neurotransmitter Release Properties by Presynaptic Calcium
Presynaptic terminals of neurons are optimized for neurotransmitter release, which is tightly controlled by presynaptic calcium. Here, we evaluate the role of calcium influx through voltage-gated calcium channels (VGCCs) ...
Nanoscale Magnetic Resonance Imaging and Magnetic Sensing Using Atomic Defects in Diamond
Magnetic resonance imaging (MRI) has revolutionized modern medicine by providing non-invasive, chemically selective, three-dimensional imaging of living organisms. Industrial-scale MRI has the capability to image with ...
Regulation of hematopoietic stem cell migration and function
Hematopoietic stem cell transplantation (HSCT) is an effective treatment for blood disorders and autoimmune diseases. Following HSCT, these cells must successfully migrate to the marrow niche and replenish the blood system ...
Genomic insights into bacterial adaptation during infection
Bacteria evolve during the colonization of human hosts, yet little is known about the selective pressures and evolutionary forces that shape this evolution. Illumination of these processes may inspire new therapeutic ...
Institutional and Cultural Roots of Industrial Development in Modern Turkey
In this dissertation I investigate the historical, institutional, and cultural roots of different regional development trajectories in modern Turkey. Historical comparison of two similar cities of 1920's, namely Kutahya ...