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Now showing items 11-18 of 18
A Clock-Phased Sigma Factor Cascade Is Required for Global Circadian Transcriptional Rhythms in Cyanobacteria
(2017-09-07)
The circadian clock of the cyanobacterium Synechococcus elongatus PCC 7942 drives oscillations in global mRNA transcript abundances with 24 h periodicity under continuous light conditions. The transcription factor RpaA ...
Circadian Clocks in the Real World: Effects of Dynamic Light Regimes on the Regulation of Circadian Gene Expression in Cyanobacteria
(2017-09-13)
Organisms use internal oscillators to control their physiology in conjunction with the predictable environmental changes of the day/night cycle. However, it is not always clear how internal timing information is used by ...
Flexible Genome Recoding Strategies for Exploring Codon Space in the Escherichia Coli Genome
(2017-01-25)
The degeneracy of the genetic code allows nucleic acids to encode amino acid identity as well as non-coding information for gene regulation and genome maintenance. This dual-nature allows for maximal information density ...
Flagellar Biosynthesis in E.coli Is Regulated by a Cascade of Stochastic Pulses
(2017-01-20)
Genetically identical populations of bacteria can exhibit significant phenotypic heterogeneity even in the absence of environmental variations. In bacteria such as Bacillus and Salmonella, flagellar motility has been found ...
Single-Molecule Studies of Bacterial Chromosome Organization and Segregation
(2017-01-04)
The bacterial chromosome is dramatically compacted into a subcellular structure called nucleoid. Simultaneously, it must be organized to allow the protein machinery for essential cellular processes to gain access to the ...
The Role of MUC5B Salivary Mucin in Modulating Oral Bacterial Surface Colonization and Interspecies Competition
(2017-04-13)
Mucus acts as a protective barrier on wet epithelial surfaces in the body including the gastrointestinal, respiratory, and reproductive tracts. A main component of mucus is mucin, which give mucus its viscoelastic properties ...
Investigating Extracellular DNA Release in Staphylococcus Aureus Biofilm Formation
(2017-01-25)
Staphylococcus aureus is a leading cause of nosocomial infections in the United States, and isolates of this pathogen are capable of forming biofilms through different mechanisms. Biofilm formation reduces susceptibility ...
Free Actin and Effects on Lung Macrophage Bacterial Defenses
(2017-02-10)
Actin release into the circulation and extracellular space, with subsequent removal by the actin scavenging protein plasma gelsolin (pGSN), has long been reported in injury and infection.
Our laboratory’s recent finding ...