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Now showing items 11-20 of 166
Bringing bioelectricity to light: all-optical electrophysiology using microbial rhodopsins
(2014-10-21)
My work has focused on the development and application of fluorescent voltage-sensitive proteins based on microbial rhodopsins. These probes led to the discovery of electrical activity in the bacterium Escherichia coli, ...
Near-surface Nitrogen Vacancy Centers in Diamond
(2014-10-21)
The nitrogen-vacancy (NV) center is a point defect in diamond and has been championed as a promising solid-state "artificial atom." NV center properties such as its bright luminescence, room-temperature optical readout of ...
The role of air in droplet impact on a smooth, solid surface
(2014-10-21)
The impact of liquid drops on solid surfaces is a ubiquitous phenomenon in our everyday experience; nevertheless, a general understanding of the dynamics governing droplet impact remains elusive. The impact event is ...
Mechanical Instabilities of Soft Materials: Creases, Wrinkles, Folds, and Ridges
(2014-10-21)
Subject to a sufficiently large compression, materials may undergo mechanical instabilities of various types. When the material is homogeneous, creases set in. When the material is a bilayer consisting of a stiff thin film ...
Controlling fluxes for microbial metabolic engineering
(2014-10-21)
This thesis presents novel synthetic biology tools and design principles usable for microbial metabolic engineering. Controlling metabolic fluxes is essential for biological manufacturing of fuels, materials, and high value ...
Accelerating Markov chain Monte Carlo via parallel predictive prefetching
(2014-10-21)
We present a general framework for accelerating a large class of widely used Markov chain Monte Carlo (MCMC) algorithms. This dissertation demonstrates that MCMC inference can be accelerated in a model of parallel computation ...
Time-Domain Fluorescence Diffuse Optical Tomography: Algorithms and Applications
(2014-10-21)
Fluorescence diffuse optical tomography provides non-invasive, in vivo imaging of molecular targets in small animals. While standard fluorescence microscopy is limited to shallow depths and small fields of view, tomographic ...
Optical Modeling of Superconducting Nanowire Single Photon Detectors
(2014-10-22)
Superconducting nanowire single photon detectors (SNSPDs) can detect single photons or low levels of infrared light in applications that require high speed and low timing jitter, such as integrated circuit analysis. Most ...
Microbial colonization and dissolution of mercury sulfide minerals
(2014-10-22)
Mercury (Hg) is a toxic heavy metal that poses significant human and environmental health risks. Mineral-associated Hg is the largest reservoir of Hg in the environment where it can account for nearly 60% of the global Hg ...
A Role for Focal Adhesions and Extracellular Matrix in Traumatic Axonal Injury
(2014-10-21)
Traumatic Brain Injury (TBI) is linked to a diverse range of diffuse pathological damage for which there is a severe lack of therapeutic options. A major limitation to drug development is the inability to identify causal ...