Antibiotic-resistant infections caused by Gram-negative pathogens pose a major threat to human health. New antibiotics to treat these infections are desperately needed. The bacterial cell wall, also known as peptidoglycan, ...

Traditional quantum algorithms with guaranteed performance generally require fully coherent quantum computers to operate, making error-correction a necessity. In contrast, variational quantum algorithms seek to remove this ...

Small molecules have powerful applications in drug discovery, target validation (or invalidation), and the study of biological mechanisms. However, the potency, selectivity, and cellular target engagement of chemical probes ...

Bioelectronics explores the use of electronic devices for applications in signal transduction at their interfaces with biological systems. Ultra-flexible nano- and micro-scale bioelectronic systems have enabled seamless ...

The Gram-positive cell wall is a massive macromolecule composed primarily of two polymers: peptidoglycan (PG) and cell wall glycopolymers. Wall teichoic acid (WTA) is the most abundant cell wall glycopolymer across ...