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Heads or Tails? Regulation of Wnt signaling and axial identity establishment during whole-body regeneration in the acoel worm Hofstenia miamia
(2020-10-06)
Whole-body regeneration relies on the re-establishment of body axes for correct patterning of tissue outgrowth. Wnt signaling is utilized to correctly regenerate tissues along the primary axis in many animals, including ...
Development and validation of computational models for efficient design of biological sequences
(2022-01-10)
There is a huge surge of interest in designing a wide variety of proteins to use as molecular research tools and biotherapeutics - promising to revolutionize our capacity to design what we need at will. This is particularly ...
The Voice of Technology: Understanding the Work of Feminine Voice Assistants and the Feminization of the Interface
(2021-06-03)
In the past decade, people have come to rely on digital voice assistants to help them interact with technology and perform tasks in every aspect of their lives. These digital voice assistants are friendly, responsive, ...
Essays in Industrial Organization
(2021-05-13)
This thesis develops methods aimed at studying transport markets, and applies them to the analysis of specific industries. The first Chapter studies platform competition in the app-based transportation industry. It presents ...
Essays in Applied Microeconomics
(2021-09-09)
This dissertation consists of three independent essays. The first essay develops an urban spatial model with heterogeneous worker groups and incorporating travel to consume non-tradable goods and services. It estimates the ...
Microbiota-Epithelial-Eosinophil Interactions in the Gut
(2022-06-06)
The gut is a critical interface between the host and its environment that requires a fine balance between nutrient absorption and barrier integrity in the face of exogenous dietary and microbial components. The intestinal ...
Controlling Gas Absorption in Liquids through Manipulation of Free Volume
(2023-03-14)
The capture, storage, and transport of gases by liquids is integral to many biological, environmental, and industrial processes. The density of gas molecules dissolved within a liquid in equilibrium with a bulk gas phase ...
Exploring the therapeutic potential of cell state specific binders to the β-barrel assembly machine
(2022-06-06)
Gram-negative bacterial infections are particularly difficult to treat as the presence of the outer membrane (OM)
makes them intrinsically resistant to many antibiotics used in the clinic. Understanding how the impermeable
OM ...
Design Principles for Improving Precision and Dexterity of Soft Robotic Hands
(2022-01-05)
As robots move more and more into the real world, they need to be equipped to interact with a wide array of objects and environment features while maintaining a gentle touch. Soft robotic end effectors enable passive ...
Computer Science on Campus: Technology, (Inter)disciplinarity, and the Transformation of the American University
(2022-05-12)
This dissertation explores how computer science became a discipline in the United States and how this process of discipline formation and institutionalization shaped the content and culture of computer science. Like other ...