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DTI PhantomMaker: A 3D-Printed DTI Calibration Phantom for Water Diffusion Direction and Anisotropy in the Brain
(2017-11-27)
As diagnostic tools, MRI scanners performing Diffusion Tensor Imaging (DTI) require calibration to ensure standardization. This thesis presents a custom-designed 3D printer used to manufacture a novel type of DTI phantom, ...
The stabilization of the Frobenius-Hecke traces on the intersection cohomology of orthogonal Shimura varieties
(2017-05-13)
The orthogonal Shimura varieties are associated to special orthogonal groups over Q of signature (n, 2) at infinity. In this work we prove a version of Morel’s formula for the Frobenius-Hecke traces on the intersection ...
Technologies for Multiplexed High Throughput Screens
(2017-10-13)
Biological processes are often far too complex to predict. For those phenomenon that still evade understanding, it is helpful to visualize a black box—a system with clear inputs and outputs, but an unknowable, labyrinthine ...
Spontaneous Emission in Nanophotonics
(2017-09-08)
In this thesis, we present semi-analytic theories of radiation noise in nanophotonic devices, which utilize new numerical software for solving light equations in nano-structures, combined with thermodynamic tools for ...
Observational Constraints on Dissipative Dark Matter
(2017-05-15)
Models for dissipative, disk-forming dark matter are explored in the context of Double Disk Dark Matter. The basics of the model are reviewed. Observational constraints are placed on the parameter space of these models. ...
Unified Viscoelastic Models of Earthquake Cycles
(2017-05-10)
Geodetic observations from before and after large earthquakes represent the opportunity to develop unified models of earthquake cycle physics that are constrained by observations that span the earthquake cycle. This thesis ...
Genetic Engineering Toward a 57-Codon Genome
(2017-01-09)
Scientific progress in fundamental biology has drastically transformed our ability to engineer biological systems, with diverse applications in medicine and industry, from insulin and artemisin production in prokaryotes ...
Determinants of Success and Failure in US Advising of Foreign Militaries, 1945-present
(2017-05-16)
Military advising is frequently touted as a high-impact, low-cost strategy that allows the United States to achieve its security goals without deploying combat troops. The US military now considers foreign military advising ...
Investigations Into DNA Double Strand Breaks in Neural Development and Function
(2017-05-12)
Genomic integrity is dependent on the repair of DNA double-strand breaks (DSBs) by classical non-homologous end-joining (C-NHEJ). C-NHEJ is essential for suppressing aberrant chromosomal rearrangements, and is also critical ...
Essays in Asset Pricing and Macroeconomics
(2017-05-13)
This dissertation presents three essays. The first essay finds that investment strategies which generate “alphas” become endogenously risky by acquiring “betas” with respect to shocks that institutional arbitrageurs are ...