Now showing items 51-55 of 55
In vitro Studies of Myofibers and Their Use in Analyzing the Differential Dynamics and Properties of α-Actinin Isoforms
Skeletal muscle is a highly organized tissue that requires cooperation of many different structures and components for proper function. We explored the use of a flexor digitorum brevis (FDB) myofiber culture system to ...
Genome Engineering Technology and Its Application in Mammalian Cells
The advancement of high-throughput, large-scale biochemical, biophysical, and genetic technologies has enabled the generation of massive amounts of biological data and allowed us to synthesize various types of biomaterial ...
Tracking Cell Fate with Synthetic Memory and Pulse Detecting Transcriptional Circuits
Synthetic biology aims to engineer biological systems to meet new challenges and teach us more about natural biological systems. These pursuits range from the building of relatively simple transcriptional circuits, to ...
Elicitation of antibody responses against the HIV-1 gp41 Membrane Proximal External Region (MPER)
An effective vaccine to protect against HIV-1/AIDS remains elusive due to the extensive mechanisms employed by the HIV-1 virus to evade immune attack. Highly potent broadly neutralizing antibodies isolated from chronically ...
The evolution and development of the archosaurian head and the origin of the bird skull
Abstract: Archosauria, the "ruling reptiles," characterized along their stem by relatively large, macrocarnivorous animals, are today represented by two enormously successful but divergent extant clades: Aves, the birds, ...